PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 14 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Rhizome essential oil and zerumbone exhibited anti-amoebic effects with an IC50 value of 87.67 ± 2.68 [PMID:41989575]
Zerumbone was found to be the most active component in cell growth inhibitory assays (IC50 13 microg mL-1) [PMID:18075886]
Hexane crude extract demonstrated good larvicidal effects with mortality observed after 24h exposure [PMID:33593018]
Evidence summary
PubMed sources
- 1.PMID: 41989575 (2026) — Essential oil of Zingiber spectabile griff.: a potential antiamoebic agent against Acanthamoeba castellanii. · Archives of microbiology
- 2.PMID: 33593018 (2017) — Efficacy of Four Species of Zingiberaceae Extract Against Vectors of Dengue, Chikungunya and Filariasis. · Tropical biomedicine
- 3.PMID: 22546674 (2012) — Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff. · Bioorganic & medicinal chemistry letters
- 4.PMID: 27330275 (2016) — Isolation and characterization of cyclo-(tryptophanyl-prolyl) and chloramphenicol from Streptomyces sp. SUK 25 with antimethicillin-resistant Staphylococcus aureus activity. · Drug design, development and therapy
- 5.PMID: 18075886