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Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Aloe vera latex (laxative) can cause potassium loss that increases sensitivity to digoxin toxicity.
Anthraquinone-induced diarrhea and potassium wasting increase myocardial sensitivity to digoxin.
Source: Natural Medicines Database · Reviewed April 2026
Aloe Vera + Digoxin: use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Aloe vera latex (laxative) can cause potassium loss that increases sensitivity to digoxin toxicity.
Anthraquinone-induced diarrhea and potassium wasting increase myocardial sensitivity to digoxin.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.