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Moderate· limited-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Cordyceps has immune-modulating properties that may interfere with immunosuppressive medications.
Cordyceps polysaccharides stimulate natural killer cells and macrophages, potentially opposing immunosuppression.
Source: Natural Medicines Database · Reviewed April 2026
Cordyceps + Immunosuppressants: use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Cordyceps has immune-modulating properties that may interfere with immunosuppressive medications.
Cordyceps polysaccharides stimulate natural killer cells and macrophages, potentially opposing immunosuppression.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.