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Sambucus nigra
Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Elderberry stimulates the immune system and may counteract immunosuppressive medications used after organ transplant or for autoimmune conditions.
Elderberry increases cytokine production (IL-1 beta, TNF-alpha, IL-6, IL-8) and activates immune cells, opposing pharmacological immunosuppression.
Source: Natural Medicines Database · Reviewed April 2026
Elderberry + Immunosuppressants (general): use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Elderberry stimulates the immune system and may counteract immunosuppressive medications used after organ transplant or for autoimmune conditions.
Elderberry increases cytokine production (IL-1 beta, TNF-alpha, IL-6, IL-8) and activates immune cells, opposing pharmacological immunosuppression.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.