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Moderate· limited-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Saw palmetto may inhibit platelet aggregation and could add to aspirin's antiplatelet effect. Discontinue before surgery and watch for unusual bruising or bleeding.
Saw palmetto fatty acids and phytosterols show mild antiplatelet activity that adds to aspirin's COX-mediated platelet inhibition.
Source: Natural Medicines Database · Reviewed September 2026
Saw Palmetto + Aspirin: use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Saw palmetto may inhibit platelet aggregation and could add to aspirin's antiplatelet effect. Discontinue before surgery and watch for unusual bruising or bleeding.
Saw palmetto fatty acids and phytosterols show mild antiplatelet activity that adds to aspirin's COX-mediated platelet inhibition.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.