Butterbur vs Nettle Leaf

Butterbur is a perennial plant native to Europe and parts of Asia, used since ancient times for plague, fever, and respiratory conditions. Modern clinical trials have established it as an effective treatment for migraine prevention and allergic rhinitis. Only PA-free (pyrrolizidine alkaloid-free) products should be used.

The aerial parts of stinging nettle used as food and medicine; leaves are highly nutritious and used for allergic rhinitis, arthritis and iron deficiency.

Petasin, Isopetasin, Oxopetasin, Flavonoids, Sesquiterpenes

quercetin, rutin, scopoletin, caffeic acid, iron, vitamin C, histamine

Plague treatment, Fever reduction, Headache relief, Respiratory support, Antispasmodic

Nutritive tonic across European and Asian medicine, Allergic rhinitis (hay fever), Iron deficiency anemia, Anti-inflammatory for arthritis

Migraine prevention, Allergic rhinitis (hay fever), Asthma, Headache prevention, Urinary spasms

Antiallergic (hay fever research), Iron-rich nutritive, Anti-inflammatory, Antioxidant

50-75mg PA-free extract twice daily for migraines

4–6 g dried leaves as tea; 300–600 mg extract 3x daily; fresh juice 30–60 mL

Liver disease, Allergy to ragweed or daisy family, Pregnancy, Non-PA-free products (liver toxicity)

Diuretic effects with concurrent medications, Kidney disease