Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Heartwood extracts and phytochemicals (e.g., melanoxetin, okanin) significantly suppressed serum uric acid levels in oxonate-induced mice by inhibiting xanthine oxidase [PMID:20806936, PMID:20047272]
Bark extract and gallic acid demonstrated hepatoprotective effects against carbon tetrachloride-induced chronic liver injury in rats [PMID:19327382]
Heartwood extracts suppressed NO production in LPS-activated macrophages [PMID:18254591]; certain bisindole alkaloids showed anti-inflammatory activity [PMID:35998213]
n-butanol-methanol extract (ACSB-M4) inhibited HCV RNA replication in a replicon assay system [PMID:21075144]
3',4',7,8-tetrahydroxyflavone inhibited RANKL-induced osteoclast formation and bone resorption in mouse bone marrow-derived macrophages [PMID:29442051]
Synthèse des preuves
Sources PubMed
- 1.PMID: 30302324 (2018) — A review of antioxidant and pharmacological properties of phenolic compounds in Acacia confusa. · Journal of traditional and complementary medicine
- 2.PMID: 35998213 (2022) — Indole alkaloids from the bark of Acacia confusa and their potential antinociceptive and anti-inflammatory activities. · Journal of Asian natural products research
- 3.PMID: 29442051 (2017) — 3',4',7,8-Tetrahydroxyflavone inhibits RANKL-induced osteoclast formation and bone resorption. · Die Pharmazie
- 4.PMID: 37110667 (2023) — Mechanistic Understanding of Tyrosinase Inhibition by Polymeric Proanthocyanidins from Acacia confusa Stem Bark and Their Effect on the Browning Resistance of Fresh-Cut Asparagus Lettuce. · Molecules (Basel, Switzerland)
- 5.PMID: 3889455