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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Cassia alata
Herbe pantropicale officiellement reconnue par le DOH des Philippines pour les affections cutanées, en particulier la teigne, le tinea et les infections fongiques.
Acapulco (Cassia alata) is a pantropical herb officially recognized by the Philippine Department of Health for treating skin conditions, particularly ringworm, tinea, and other fungal infections. Its primary uses leverage antifungal, antibacterial, anti-inflammatory, and keratolytic properties, attributed to active compounds such as chrysophanol, physcion, aloe-emodin, kaempferol, and sennosides. Evidence level C supports its modern topical application, while traditional use extends to eczema and psoriasis.
The antifungal activity of Cassia alata is primarily mediated by anthraquinones (chrysophanol, physcion, aloe-emodin) that disrupt fungal cell wall synthesis and membrane integrity, likely through inhibition of chitin synthase and ergosterol biosynthesis. Kaempferol contributes anti-inflammatory effects by inhibiting cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene production. The keratolytic action is attributed to sennosides and other anthraquinones promoting desquamation of the stratum corneum, while antibacterial effects involve disruption of bacterial cell membranes and inhibition of nucleic acid synthesis.
Herbe pantropicale officiellement reconnue par le DOH des Philippines pour les affections cutanées, en particulier la teigne, le tinea et les infections fongiques.
Acapulco (Cassia alata) is a pantropical herb officially recognized by the Philippine Department of Health for treating skin conditions, particularly ringworm, tinea, and other fungal infections. Its primary uses leverage antifungal, antibacterial, anti-inflammatory, and keratolytic properties, attributed to active compounds such as chrysophanol, physcion, aloe-emodin, kaempferol, and sennosides. Evidence level C supports its modern topical application, while traditional use extends to eczema and psoriasis.
The antifungal activity of Cassia alata is primarily mediated by anthraquinones (chrysophanol, physcion, aloe-emodin) that disrupt fungal cell wall synthesis and membrane integrity, likely through inhibition of chitin synthase and ergosterol biosynthesis. Kaempferol contributes anti-inflammatory effects by inhibiting cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene production. The keratolytic action is attributed to sennosides and other anthraquinones promoting desquamation of the stratum corneum, while antibacterial effects involve disruption of bacterial cell membranes and inhibition of nucleic acid synthesis.