Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
How does Amorphophallus konjac work for weight loss?
Konjac works primarily through its active component, glucomannan, a highly viscous soluble fiber. When ingested with water, it expands in the stomach to form a bulky gel, delaying gastric emptying and increasing satiety. This physical action reduces overall calorie intake. Additionally, it slows glucose absorption in the intestines, contributing to better blood sugar management. Evidence Level: C.
Does konjac glucomannan interact with prescription medications?
Yes, konjac can interact with oral medications. Because glucomannan slows digestion, it may reduce the absorption rate and efficacy of certain drugs, particularly oral hypoglycemic agents. To minimize this risk, separate the intake of konjac supplements and prescription medications by at least one to two hours. Consult a physician before combining supplements with medication. Evidence Level: C.
What is the correct dosage for Amorphophallus konjac supplements?
The standard adult dosage ranges from 1 to 4 grams of glucomannan daily, taken before meals. It is critical to take each dose with a full glass of water to prevent the fiber from expanding in the esophagus or throat. Without adequate hydration, the supplement poses a risk of physical blockage. Evidence Level: C.
Is it safe to take konjac root during pregnancy?
Amorphophallus konjac is considered unsafe during pregnancy. The high fiber content can cause significant gastrointestinal distress, including bloating and potential bowel obstruction, which may complicate pregnancy. Furthermore, the satiating effects may lead to reduced nutritional intake essential for fetal development. Pregnant women should avoid glucomannan supplements unless directed otherwise by a healthcare professional. Evidence Level: C.
What are the dangers of taking konjac without water?
Taking konjac glucomannan without sufficient water is dangerous because the fiber can expand in the throat or esophagus before reaching the stomach. This can cause life-threatening esophageal obstruction or choking. Individuals with dysphagia or existing esophageal strictures should avoid this herb entirely. Always consume konjac with at least 8 ounces of fluid. Evidence Level: C.
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 29 articles PubMed · modèle : gemma4:31b
Résumé
Amorphophallus konjac is a perennial herb from the Araceae family, primarily valued for its bioactive polysaccharide, konjac glucomannan (KGM) [PMID:35242290, PMID:40117876].
Contexte
Amorphophallus konjac is a perennial tuberous plant native to Southeast Asia [PMID:40061034, PMID:39478464]. It is an economically important crop used in health products, biomaterials, and as a food source [PMID:38114626, PMID:20079822].
Usages traditionnels
In traditional Chinese medicine, konjac gel has been used for detoxification, tumor-suppression, blood stasis alleviation, and phlegm liquefaction; it has also been used for over 2000 years to treat asthma, cough, hernia, breast pain, burns, and haematological and skin disorders [PMID:20079822]. The genus is also used in Ayurveda and Unani medical practices [PMID:38068582].
Composés actifs
The primary bioactive component is konjac glucomannan (KGM), a soluble, highly viscous dietary fiber polysaccharide derived from the corm/root [PMID:30000957, PMID:29606469, PMID:40117876]. The plant also contains polyphenolic compounds, alkaloids, steroids, fats, fixed oils, tannins, proteins, and carbohydrates [PMID:38068582].
Mécanisme d'action
KGM may promote weight loss by promoting satiety and fecal energy loss [PMID:16320857]. It can form a defensive covering on the surface of the intestine [PMID:30586587] and may exert prebiotic effects through colonic fermentation into short-chain fatty acids (SCFAs) [PMID:26676961, PMID:29971989]. In animal models, KGM has been shown to promote lymphocyte proliferation and increase cytokine levels (TNF-α, IgG, IL-2) [PMID:33598158].
Preuves cliniques
Preuve CObesity/Weight Management
Doses of 2-4 g per day resulted in significant weight loss in overweight and obese individuals [PMID:16320857].
Preuve CMetabolic Health
KGM has been shown to improve lipid and lipoprotein parameters, glycemic status, and reduce cholesterol, triglycerides, and blood pressure [PMID:16320857, PMID:30586587, PMID:38823930].
Preuve CDiabetes
KGM is used to treat diabetes and stabilize blood glucose [PMID:30000957, PMID:40061034].
Preuve CConstipation
KGM is used to treat constipation [PMID:30000957].
Sécurité et effets indésirables
KGM is reported to be well-tolerated at doses of 2-4 g per day [PMID:16320857]. It is described as having low toxicity and high biocompatibility [PMID:24607175, PMID:38320637].
Grossesse et allaitement
No data exist on the safety and efficacy of glucomannan in nursing mothers or infants; however, because it is not absorbable, it is unlikely to reach breastmilk or affect the nursing infant [PMID:30000957].
Synthèse des preuves
The evidence is primarily based on reviews and animal studies (Level C and D), with some preliminary clinical evidence for weight loss and metabolic improvement.
Sources PubMed
1.PMID: 30000957 (2006) — Konjac glucomannan, a promising polysaccharide of Amorphophallus konjac K. Koch in health care. · International journal of biological macromolecules
2.PMID: 26676961 (2016) — Beneficial health characteristics of native and hydrolysed konjac (Amorphophallus konjac) glucomannan. · Journal of the science of food and agriculture
3.PMID: 38114626 (2023) — Characteristics of Amorphophallus konjac as indicated by its genome. · Scientific reports
4.PMID: 32603265 (2020) — Taro koji of Amorphophallus konjac enabling hydrolysis of konjac polysaccharides to various biotechnological interest. · Bioscience, biotechnology, and biochemistry
5.PMID: 35242290 (2022) — A chromosome-level genome assembly of Amorphophallus konjac provides insights into konjac glucomannan biosynthesis.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
· Computational and structural biotechnology journal
6.PMID: 29606469 (2018) — Modifications of konjac glucomannan for diverse applications. · Food chemistry
7.PMID: 16320857 (2005) — Glucomannan and obesity: a critical review. · Alternative therapies in health and medicine
8.PMID: 33598158 (2021) — Konjac Glucomannan from Amorphophallus konjac enhances immunocompetence of the cyclophosphamide-induced immunosuppressed mice. · Food science & nutrition
9.PMID: 40061034 (2025) — Amorphophallus konjac: traditional uses, bioactive potential, and emerging health applications. · Frontiers in plant science
10.PMID: 35808596 (2022) — Review on Modification of Glucomannan as an Excipient in Solid Dosage Forms. · Polymers
11.PMID: 29971989 (2018) — Depolymerized konjac glucomannan: preparation and application in health care. · Journal of Zhejiang University. Science. B
12.PMID: 37473898 (2023) — Konjac glucomannan-based hydrogels with health-promoting effects for potential edible electronics applications: A mini-review. · International journal of biological macromolecules
13.PMID: 24607175 (2014) — Konjac glucomannan, a promising polysaccharide for OCDDS. · Carbohydrate polymers
14.PMID: 38068582 (2023) — Genus Amorphophallus: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities. · Plants (Basel, Switzerland)
15.PMID: 38320637 (2024) — Advances in the construction and application of konjac glucomannan-based delivery systems. · International journal of biological macromolecules
16.PMID: 30586587 (2019) — Health-promoting effects of konjac glucomannan and its practical applications: A critical review. · International journal of biological macromolecules
18.PMID: 40117876 (2025) — Extraction, structure, activity and application of konjac glucomannan. · Ultrasonics sonochemistry
19.PMID: 38823930 (2024) — Konjac glucomannan: A comprehensive review of its extraction, health benefits, and pharmaceutical applications. · Carbohydrate polymers
20.PMID: 39478464 (2024) — Genome-wide analysis of the Amorphophallus konjac AkCSLA gene family and its functional characterization in drought tolerance of transgenic arabidopsis. · BMC plant biology
21.PMID: 20079822 (2010) — Traditional uses and potential health benefits of Amorphophallus konjac K. Koch ex N.E.Br. · Journal of ethnopharmacology