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Artemisia roxburghiana
Artemisia roxburghiana
Affections digestives en médecine traditionnelle himalayenne
PubMed · Bioprospecting <i>Artemisia roxburghiana</i> Wall. ex Besser extracts for their potential antimicrobial, antiprotozoal, antidiabetic and anticancer potential. (2025)
PubMed · A new guaianolide from Artemisia roxburghiana. (2013)
Révisé par : HerbAlly Editorial Team, Medical herbalists and healthcare professionals
Dernière mise à jour : April 2026
Calculer une dose sûre de Artemisia roxburghiana
Calculateur gratuit de posologie — doses adultes et enfants selon le poids.
Artemisia roxburghiana contains bioactive compounds including camphor, terpineol, thujone, and flavonoids that contribute to its medicinal effects. The volatile oils act as carminatives, helping to relax digestive smooth muscle and reduce gas and bloating. The flavonoids and terpenoids demonstrate anti-inflammatory activity by modulating inflammatory pathways. Thujone and other constituents may also provide respiratory benefits through bronchodilatory and antimicrobial effects. Evidence level: C (preliminary studies and traditional use).
Does Artemisia roxburghiana interact with any medications?
Artemisia roxburghiana may interact with several medication classes due to its thujone content and effects on liver metabolism. It may potentially interact with anticonvulsant medications, as thujone can lower seizure threshold. Those taking CNS depressants, blood thinners, or medications metabolized by liver enzymes should exercise caution. Limited clinical data exists on specific drug interactions. Patients taking prescription medications should consult a healthcare provider before using this herb. Evidence level: C.
What is the recommended dosage of Artemisia roxburghiana?
The traditional adult dosage for Artemisia roxburghiana is 2-4 grams of dried herb prepared as a tea, taken up to three times daily for digestive or respiratory complaints. This dosage is based on Himalayan folk medicine traditions rather than clinical trials. Liquid extracts and tinctures may have different concentration-based dosing. Always follow product label instructions or consult a qualified herbalist, as individual needs may vary. Evidence level: Traditional/C.
Is Artemisia roxburghiana safe during pregnancy and breastfeeding?
Artemisia roxburghiana is contraindicated during pregnancy and breastfeeding. The herb contains thujone, a compound that can stimulate uterine contractions and potentially cause miscarriage or premature labor. Thujone may also be neurotoxic to developing fetuses and infants. Women who are pregnant, planning pregnancy, or breastfeeding should avoid this herb entirely. Additionally, individuals with epilepsy should not use this herb due to thujone's potential to lower seizure threshold. Evidence level: C.
What is Artemisia roxburghiana used for in traditional medicine?
Artemisia roxburghiana has been used traditionally in Himalayan folk medicine primarily for digestive and respiratory conditions. As a carminative, it helps relieve gas, bloating, and indigestion. Traditional uses include treating coughs, bronchitis, and other respiratory complaints. The herb also has anti-inflammatory properties that may support its traditional applications. These uses are based on ethnobotanical knowledge and preliminary research rather than large-scale clinical trials. Evidence level: C/Traditional.
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 13 articles PubMed · modèle : gemma4:31b
Résumé
Artemisia roxburghiana is a medicinal herb found in high-altitude regions of the Himalayas and other areas, traditionally used to treat diabetes and various infections [PMID:39665106, 40024454].
Contexte
Artemisia roxburghiana is a herbaceous plant that serves as a dominant genus in the alpine ecosystems of the cold desert region in the Western Himalayas, specifically the Nelang Valley [PMID:39665106]. It is also found in Vietnam and northern Punjab, Pakistan [PMID:23432134, 26691254].
Usages traditionnels
In the Himalayan region, it is used as a remedy for fever, diabetes, malaria, dysentery, rheumatism, and viral hepatitis [PMID:40024454]. It is also used in the Indian subcontinent for the management of diabetes mellitus [PMID:33331175].
Composés actifs
The plant contains terpenoids, glycosides, tannins, saponins [PMID:41404792], and artemisinins [PMID:41404792]. Specific isolated compounds include betulinic acid, betulin, taraxeryl acetate [PMID:26118418], 11-epi-8α-hydroxyarborescin, (24R)- and (24S)-cycloart-25-en-3b,24-diols, palmitic acid, and 1-octacosanol [PMID:23432134]. It also exhibits high total phenol content (93.4 ± 0.53 µg GAE/mg) and total flavonoid content (23.22 ± 0.23 µg CE/mg) [PMID:41844424].
Mécanisme d'action
The herb exhibits antidiabetic activity by inhibiting α-glucosidase and α-amylase enzymes [PMID:33331175]. Certain triterpene inhibitors (betulinic acid, betulin, and taraxeryl acetate) act as protein tyrosine phosphatase 1B (PTP1B) inhibitors, interacting with Gly220, Cys215, Gly218, and Asp48 [PMID:26118418].
Preuves cliniques
Preuve DDiabetes Mellitus
Aqueous-ethanol extract of aerial parts showed a significant glucose-lowering effect in streptozotocin-nicotinamide-induced diabetic Wistar rats at doses of 200 and 400 mg/kg [PMID:33331175].
Preuve DGastrointestinal Nematodes
Methanolic extracts showed maximum anthelmintic activity at a concentration of 50 mg/ml in an in vitro egg hatch inhibition assay [PMID:26691254].
Preuve DMalaria/Protozoal Infections
Extracts demonstrated antimalarial activity (IC50=18.76 ± 1.80 µg/mL) and general antiprotozoal activity [PMID:41404792, 21527328].
Sécurité et effets indésirables
Acute and sub-acute toxicity was evaluated in albino mice using aqueous leaf extract; however, the provided abstract does not list specific adverse findings, only the parameters assessed (body weight, hematological, and biochemical parameters) [PMID:40024454].
Synthèse des preuves
The current evidence is primarily based on in vitro studies and animal models (Level D), demonstrating potential antidiabetic, antimicrobial, and anthelmintic activities.
Sources PubMed
1.PMID: 39665106 (2024) — Floristic diversity and species composition along altitudinal gradient in the alpine ecosystem of the cold desert region in Western Himalaya, India. · Frontiers in plant science
2.PMID: 41404792 (2025) — Bioprospecting Artemisia roxburghiana Wall. ex Besser extracts for their potential antimicrobial, antiprotozoal, antidiabetic and anticancer potential. · Natural product research
3.PMID: 26118418 (2016) — Protein tyrosine phosphatase 1B inhibitors isolated from Artemisia roxburghiana. · Journal of enzyme inhibition and medicinal chemistry
4.PMID: 23432134 (2013) — A new guaianolide from Artemisia roxburghiana. · Natural product research
5.PMID: 33331175 (2022) — Antidiabetic effect of aqueous-ethanol extract from the aerial parts of Artemisia roxburghiana.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 21527328 (2011) — Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, India. · Journal of ethnopharmacology
7.PMID: 40024454 (2025) — Toxicological assessment of standardized Artemisia roxburghiana wall. ex Besser aqueous leaf extract to acute and subacute exposure in Albino mice. · Journal of ethnopharmacology
8.PMID: 26691254 (2015) — Anthelmintic properties of extracts from Artemisia plants against nematodes. · Tropical biomedicine
9.PMID: 41844424 (2026) — Synthesis and characterization of zinc oxide nanoparticles by the aerial part of Artemisia roxburghiana extract and assessment of their biological activities. · Zeitschrift fur Naturforschung. C, Journal of biosciences
10.PMID: 21047440 (2010) — Survey of artemisinin production by diverse Artemisia species in northern Pakistan. · Malaria journal
11.PMID: 36081821 (2022) — Formulation and evaluation of SGLT2 inhibitory effect of a polyherbal mixture inspired from Ayurvedic system of medicine. · Journal of traditional and complementary medicine
12.PMID: 19143344 (2008) — Restoration potential of pioneer plants growing on lead-zinc mine tailings in Lanping, southwest China. · Journal of environmental sciences (China)
13.PMID: 14750205 (2004) — The effect of medicinal plants of Islamabad and Murree region of Pakistan on insulin secretion from INS-1 cells. · Phytotherapy research : PTR