Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Astragalus sinicus, also known as Chinese milk vetch, is a legume primarily used as a green manure to improve soil fertility and rice productivity [PMID:35602334, 35529952]. Recent research has explored its potential in phytoremediation of heavy metals and as a treatment for menopause-related symptoms [PMID:38202384, 41605805].
Contexte
Astragalus sinicus (Chinese milk vetch) is a traditional winter-growing cover crop and green manure species widely planted in the temperate zones of China [PMID:35602334, 36466260]. It is used to upgrade soil fertility, maintain crop yield and quality in rice fields, and as a landscape ground cover plant [PMID:35602334, 37510305].
Usages traditionnels
Primarily utilized as a green manure and cover crop to improve rice productivity and prevent soil degeneration [PMID:35529952].
Composés actifs
Water-extractable organic matter from A. sinicus is rich in C=C and C=O functional groups, including carboxylic acids, alcohols, phenols, fatty acids, aliphatic aromatic, and amide compounds [PMID:32126945]. It also contains anthocyanins, the formation of which depends on the enzyme chalcone isomerase (CHI) [PMID:37510305].
Mécanisme d'action
In an ovariectomized mouse model, A. sinicus ethanol extract exhibited estrogenic activity and improved the mRNA expression of menopause-related genes [PMID:41605805]. In soil, its decomposition leachates contain compounds that exert phytotoxicity on weeds like goosegrass [PMID:36466260].
Preuves cliniques
Preuve DMenopausal symptoms
Ethanol extract of A. sinicus effectively improved menopause-related symptoms in an ovariectomized (OVX) mouse model and showed estrogenic activity in vitro [PMID:41605805]
Synthèse des preuves
The majority of available evidence is based on agricultural and botanical research (soil science, genomics, and phytoremediation). There is very limited preclinical evidence (animal/in vitro models) regarding its potential medicinal use for menopausal symptoms.
Sources PubMed
- 1.PMID: 35574090 (2022) — Astragalus sinicus Incorporated as Green Manure for Weed Control in Corn. · Frontiers in plant science
- 2.PMID: 38202384 (2023) — Cadmium-Tolerant Bacterium Strain Cdb8-1 Contributed to the Remediation of Cadmium Pollution through Increasing the Growth and Cadmium Uptake of Chinese Milk Vetch (Astragalus sinicus L.) in Cadmium-Polluted Soils. · Plants (Basel, Switzerland)
- 3.PMID: 40871297 (2025) — Biochar-Immobilized Pseudomonas aeruginosa Enhances Copper Remediation and Growth of Chinese Milk Vetch (Astragalus sinicus). · Microorganisms
- 4.PMID: 35602334 (2022) — The complete chloroplast genome and phylogenetic analysis of Astragalus sinicus Linne 1767. · Mitochondrial DNA. Part B, Resources
- 5.PMID: 35185950 (2021) — Synergism Between Water Management and Phosphorus Supply Enhances the Nodulation and Root Growth and Development of Chinese Milk Vetch (Astragalus sinicus L.).