Bai He (Lilium lancifolium): Benefits, Dosage, Safety & Evidence

Questions fréquentes

What is Bai He used for in Traditional Chinese Medicine?

Bai He is primarily used in Traditional Chinese Medicine to nourish lung yin and calm the heart-mind. It is commonly prescribed for lung yin deficiency presenting as dry cough with scanty sputum, chronic cough, or hemoptysis. The herb also addresses emotional conditions including anxiety, restlessness, and insomnia. Its demulcent properties help soothe irritated respiratory mucous membranes. Evidence level: C, based primarily on traditional use and clinical observation rather than randomized controlled trials.

How does Bai He work to treat cough and anxiety?

Bai He contains active compounds including colchicine, regaogenin, tuliposides, and flavonoids that contribute to its therapeutic effects. As a demulcent, it forms a soothing protective layer over mucous membranes in the respiratory tract, reducing irritation and dryness. In TCM theory, Bai He nourishes lung yin to address dry cough while simultaneously calming the heart-mind to relieve anxiety and insomnia. The flavonoids provide additional antioxidant support. Evidence level: C.

What is the recommended dosage for Bai He?

The typical adult dosage of Bai He ranges from 9-30 grams daily, depending on the condition being treated and the formulation used. Lower doses around 9-15 grams are common for mild symptoms, while higher doses up to 30 grams may be appropriate for more severe lung yin deficiency. Bai He is typically prepared as a decoction or added to medicinal soups. Evidence level: C. Consult a qualified TCM practitioner for personalized dosing recommendations.

Is Bai He safe to take during pregnancy?

Bai He is considered unsafe during pregnancy and should be avoided. The herb contains colchicine, a compound that may pose risks to fetal development and could affect uterine function. Breastfeeding women should also avoid Bai He, as active compounds may pass into breast milk. Women who are pregnant, trying to conceive, or breastfeeding should not use this herb without explicit guidance from a qualified healthcare provider. Evidence level: C.

Does Bai He interact with any medications?

Bai He contains colchicine, which may interact with medications metabolized by the liver or drugs affecting blood cell counts. Caution is warranted when combining Bai He with immunosuppressants, anticoagulants, or other herbs containing colchicine-like compounds. Patients taking prescription medications should consult a qualified healthcare practitioner before using Bai He, as clinical interaction data is limited. Evidence level: C. Those with cold conditions should avoid this herb as it may exacerbate symptoms.

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Lilium lancifolium (Bai He) is a medicinal and edible plant native to Northeast Asia used traditionally for pulmonary ailments, depression, and blood glucose management [PMID:32173873, 39539631, 42338973].

Contexte

Lilium lancifolium Thunb., also known as tiger lily, is a perennial bulbous plant native to Northeast Asia [PMID:32173873, 41368573]. It is cultivated as a cash crop in China and is valued for its ornamental, medicinal, and edible properties [PMID:36386686, 35462288].

Usages traditionnels

Traditionally used in China and Korea to treat bronchitis, pneumonia, and other pulmonary ailments [PMID:23796878]. It is also used to 'moisten the lungs, relieve coughs, and calm the mind to soothe the heart' [PMID:41375993], and has been used in folk medicine to help lower blood glucose levels [PMID:42338973].

Composés actifs

Active components include polysaccharides (such as LLP-1A and L005-B) [PMID:28898768, 40114341], steroidal glycosides (including lililancifoloside B, C, D, and E) [PMID:38168567], and phenolic compounds such as regaloside A, regaloside B, regaloside E, p-coumaric acid, ferulic acid, and chlorogenic acid [PMID:32173873, 35462288, 37372556].

Mécanisme d'action

The herb exhibits anti-inflammatory effects by inhibiting pro-inflammatory protein expressions through the MyD88 dependent pathway [PMID:32173873]. Polysaccharides (LLP-1A) enhance macrophage phagocytic activity and induce the production of NO and cytokines including IL-6, MCP-1, TNF-α, and IL-1β [PMID:28898768]. Flower-derived polysaccharides (L005-B) alleviate pulmonary fibrosis by inhibiting epithelial-mesenchymal transition and reducing fibrosis-associated proteins like fibronectin, collagen, and α-SMA [PMID:40114341].

Preuves cliniques

Preuve CDepression

Baihe Dihuang Decoction (containing L. lancifolium) is effective in treating depression [PMID:39539631].

Preuve DPulmonary Inflammation

Root extract attenuated pulmonary inflammation and air space enlargement in cigarette smoke-exposed mouse models [PMID:23796878].

Preuve DHyperglycemia

Extracts from L. lancifolium exhibit potent hypoglycemic activity [PMID:42338973].

Preuve DOsteoarthritis

Long-term intake of L. lancifolium extract mitigated osteoarthritic effects by suppressing inflammatory cytokines in a dog model [PMID:36313850].

Preuve DPulmonary Fibrosis

A novel polysaccharide (L005-B) from flowers improved bleomycin-induced histopathological changes and attenuated pulmonary index and hydroxyproline contents in vivo [PMID:40114341].

Preuve DCancer (In Vitro)

Certain steroidal glycosides (specifically compound 6) showed cytotoxic activity against MCF-7, MDA-MB-231, HepG2, and A549 cell lines, inducing G2/M phase arrest and apoptosis in HepG2 cells [PMID:38168567].

Synthèse des preuves

The evidence consists primarily of in vitro studies, animal models (mice, dogs), and literature reviews. There is a lack of high-level human clinical trial data (RCTs) in the provided abstracts.

Sources PubMed

1.PMID: 32173873 (2020) — Antioxidant and anti-inflammatory effects of Lilium lancifolium bulbs extract. · Journal of food biochemistry
2.PMID: 39539631 (2024) — Rehmannia glutinosa DC.-Lilium lancifolium Thunb. in the treatment of depression: a comprehensive review and perspectives. · Frontiers in pharmacology
3.PMID: 28898768 (2017) — Immune-enhancing effects of polysaccharides extracted from Lilium lancifolium Thunb. · International immunopharmacology
4.PMID: 42338973 (2026) — The hypoglycemic metabolites and potential mechanisms of Lilium lancifolium (Juandan lily). · Frontiers in pharmacology
5.PMID: 36386686 (2022) — Rhizospheric microbial consortium of Lilium lancifolium Thunb. causes lily root rot under continuous cropping system. · Frontiers in microbiology

Bai He

Sources et citations

Calculer une dose sûre de Bai He

Passiflora Quadrangularis

Albizia

Duoc Lieu Trinh Nu

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Bai He

Sources et citations

Calculer une dose sûre de Bai He

Plantes associées

Passiflora Quadrangularis

Albizia

Duoc Lieu Trinh Nu

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales