Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Betula alba (white birch) is a tree species whose extracts are used in traditional medicine and dermocosmetics [PMID:30106978, PMID:21709432].
Contexte
Betula alba, also known as white birch, is a tree species [PMID:23369181]. It is closely related to other birch species such as Betula pendula (silver birch) and Betula platyphylla [PMID:36394364].
Usages traditionnels
Birch buds (Gemmae Betulae) are used in Russian and Chinese traditional medicine primarily as diuretic and diaphoretic agents, as well as for antiseptic, anti-inflammatory, and analgesic purposes [PMID:30106978].
Composés actifs
Bark and leaves of Betula alba contain cyclic diarylheptanoid glucosides, diarylheptanoids, phenylethanoids, methyl salicylate glycosides, dihydrobenzofuran glucosides, arylbutanoid glycosides, lignan glycosides, flavanone glucosides, and triterpenes [PMID:33121272]. Betulinic acid, a pentacyclic triterpenoid, is found in Betula alba bark [PMID:29784509].
Mécanisme d'action
Certain compounds from B. alba bark and leaves (specifically compounds 14 and 17-20) exhibit inhibitory activity against aldose reductase (AR) [PMID:33121272]. Betulinic acid-loaded nanoparticles have been shown to reduce the pro-parasitic, anti-inflammatory cytokine IL-10 and increase nitric oxide (NO) production in L. donovani-infected macrophages [PMID:29784509].
Preuves cliniques
Preuve CDry skin
Topical application of Betula alba birch bark extract increased skin hydration, reduced transepidermal water loss, or promoted keratinocyte differentiation in humans in vivo [PMID:21709432]
Sécurité et effets indésirables
Birch (Betula alba) is used as a standard allergen extract in European skin prick tests to confirm IgE-mediated allergic sensitization [PMID:23369181].
Synthèse des preuves
The evidence is primarily based on phytochemical analysis, in vitro studies, and a review of dermocosmetic ingredients, with limited clinical data provided in the abstracts.
Sources PubMed
- 1.PMID: 23369181 (2013) — The skin prick test - European standards. · Clinical and translational allergy
- 2.PMID: 36394364 (2023) — Genomic signals of local adaptation and hybridization in Asian white birch. · Molecular ecology
- 3.PMID: 30106978 (2018) — Cytotoxicity of white birch bud extracts: Perspectives for therapy of tumours. · PloS one
- 4.PMID: 21709432 (2011) — Dermocosmetics for dry skin: a new role for botanical extracts. · Skin pharmacology and physiology
- 5.PMID: 33121272 (2022) — Chemical constituents and aldose reductase inhibitory activities of Betula alba bark and leaves. · Natural product research