Fiche d'information compilée à partir de PubMed
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Compilé à partir de 20 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Preuves cliniques
Hexane extract from leaves exhibited strong in vitro activity against chloroquine sensitive (CQS) strain (IC50 2.53 microg/mL); isolated compounds muzigadial showed the strongest activity (IC50 0.31 microg/mL) [PMID:21299109]
Drimane sesquiterpenoids showed cytotoxicity in Chinese Hamster Ovarian (CHO) cells, with muzigadial exhibiting an IC50 of 1.18 microg/mL [PMID:21299109]. Extracts were also evaluated for cytotoxic effects against Artemia salina and breast cancer cell lines [PMID:25856874]
Canellal and an essential oil fraction from Canella winterana were tested for antimycobacterial activity, though they were not listed among the compounds that showed activity [PMID:9626931]
Synthèse des preuves
Sources PubMed
- 1.PMID: 9626931 (1998) — Antimycobacterial activity of chemically defined natural substances from the Caribbean flora in Guadeloupe. · FEMS immunology and medical microbiology
- 2.PMID: 25856874 (2015) — Biological screening of select Puerto Rican plants for cytotoxic and antitumor activities. · Puerto Rico health sciences journal
- 3.PMID: 30801919 (2019) — Implication of palynological techniques for the authentication of adulterated drugs traded with the same name in different herbal markets of district Lahore, Pakistan. · Microscopy research and technique
- 4.PMID: 21299109 (2010) — Antiplasmodial and cytotoxic activities of drimane sesquiterpenes from Canella winterana. · Natural product communications
- 5.PMID: 11354963