Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Cardamom functions primarily as a carminative, helping to relieve intestinal gas and bloating. Its active compound, cineole, exhibits antispasmodic effects that relax smooth muscles in the gut, reducing cramping. Additionally, it stimulates digestive enzyme secretion, which facilitates the breakdown of food. These combined actions make it effective for managing dyspepsia and flatulence (Evidence Level C/Traditional).
Is cardamom safe to use during pregnancy?
Cardamom is considered unsafe for medicinal use during pregnancy. While culinary amounts used as a spice are generally acceptable, therapeutic doses may stimulate uterine contractions due to its antispasmodic properties. Pregnant women should avoid concentrated supplements or extracts. Those breastfeeding should also exercise caution due to insufficient safety data regarding therapeutic doses (Evidence Level C).
What is the recommended daily dosage for cardamom seeds?
The standard recommended dosage for adults is 1 to 3 grams of whole pods or crushed seeds daily. This amount is typically used to manage digestive complaints like nausea or flatulence. It can be consumed as a powder, chewed directly, or brewed as a tea. Dosage for children has not been rigorously established (Evidence Level C).
Does cardamom interact with prescription medications?
There are currently no well-documented severe drug interactions for culinary doses of cardamom. However, high therapeutic doses may theoretically affect liver enzymes (CYP450), potentially altering the metabolism of certain drugs. Patients taking anticoagulants or medications with narrow therapeutic indices should consult a healthcare provider before using concentrated cardamom supplements (Evidence Level C).
Who should avoid taking cardamom?
Individuals with gallstones should avoid medicinal doses of cardamom. The herb stimulates bile secretion, which could potentially cause stones to obstruct the bile ducts, leading to severe complications. Additionally, those with allergies to plants in the Zingiberaceae family, such as ginger or turmeric, should exercise caution. Generally, side effects are rare but may include contact dermatitis (Evidence Level C).
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 29 articles PubMed · modèle : gemma4:31b
Résumé
Cardamom (Elettaria cardamomum) is a nutraceutical spice with documented antioxidant, anti-inflammatory, and metabolic activities [PMID:36835337, PMID:35317114].
Contexte
Elettaria cardamomum, known as small or true cardamom, is a perennial herbaceous plant of the Zingiberaceae family native to Southern India [PMID:37235027, PMID:28070488]. It is highly valued globally for its aroma and taste, often used as a flavoring in sweets, baked goods, and coffee [PMID:7039980, PMID:37235027].
Usages traditionnels
Traditionally used in Ayurvedic and Unani medicine for female reproductive health [PMID:38558676], gastrointestinal disorders [PMID:16298093], asthma, teeth and gum infections, cataracts, nausea, diarrhea, and cardiac or kidney disorders [PMID:31541721]. It has also been used during breastfeeding for infant colic and as a galactogogue [PMID:40460231].
Composés actifs
Major components include alpha-terpinyl acetate and 1,8-cineole [PMID:40460231, PMID:39861065]. Other identified compounds include limonene, cymene, pinene, linalool, borneol, cardamonin, indole-3-carbinol, and diindolylmethane [PMID:39334932], as well as various phenolic compounds and water-soluble alpha-glucans [PMID:35317114, PMID:23795480].
Mécanisme d'action
Cardamom exerts anti-inflammatory effects by lowering the expression of pro-inflammatory genes such as NFkB, TNF-alpha, IL-6, and COX2 through the reduction of reactive oxygen species (ROS) [PMID:37447289, PMID:34579443]. In mice, it modulates the neuroendocrine axis to regulate food intake, energy expenditure, and adipose tissue lipolysis [PMID:36835337]. It may also target the programmed cell death lignin-1 gene in cancer cells [PMID:39334932].
Preuves cliniques
Preuve DObesity/Weight Management
Intake in mice increased energy expenditure, reduced fat mass, and increased lean mass [PMID:36835337]
Preuve DHypercholesterolemia
Oral administration of cardamom oil in rats significantly reduced total cholesterol (31%), LDL cholesterol (44%), and serum triglycerides (42%) [PMID:27888503]
Preuve DGastric Ulcers
Methanolic extracts and essential oils significantly inhibited gastric lesions induced by ethanol and aspirin in rats [PMID:16298093]
Preuve DPeriodontal Infections
Fruit and seed extracts showed antibacterial effects against pathogens including P. gingivalis and inhibited biofilm formation [PMID:31430531]
Preuve DCancer (Ehrlich solid tumors)
Green cardamom alone or combined with cyclophosphamide reduced tumor size and inhibited tumor growth in mice [PMID:33926427]
Preuve DAnxiety-like behavior (PTSD model)
Sécurité et effets indésirables
Cardamom is listed as a rare trigger for anaphylaxis [PMID:29214141].
Grossesse et allaitement
Used during breastfeeding as a treatment for infant colic and as a galactogogue [PMID:40460231].
Synthèse des preuves
The majority of evidence is derived from in vitro studies and animal models (Level D), with some narrative and systematic reviews (Level C) summarizing these findings. Human clinical data are limited or inconclusive.
Sources PubMed
1.PMID: 38558676 (2024) — Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health. · Cureus
2.PMID: 40460231 (2006) — Functional foods modulating inflammation and metabolism in chronic diseases: a systematic review. · Critical reviews in food science and nutrition
3.PMID: 36835337 (2023) — Cardamom (Elettaria cardamomum (L.) Maton) Seeds Intake Increases Energy Expenditure and Reduces Fat Mass in Mice by Modulating Neural Circuits That Regulate Adipose Tissue Lipolysis and Mitochondrial Oxidative Metabolism in Liver and Skeletal Muscle. · International journal of molecular sciences
4.PMID: 35174687 (2022) — Effectiveness of cardamom (Elettaria cardamomum) or bay leaf (Laurus nobilis L.) powder in improving the quality of Labneh. · Acta scientiarum polonorum. Technologia alimentaria
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
Methanolic extract (particularly at 400mg/kg) showed efficacy in reducing anxiety-like behavior in rats [PMID:28073098]
— The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review.
· Iranian journal of basic medical sciences
6.PMID: 33926427 (2021) — Effects of Green cardamom (Elettaria cardamomum Maton) and its combination with cyclophosphamide on Ehrlich solid tumors. · BMC complementary medicine and therapies
7.PMID: 39861065 (2024) — Multivalent Neuroprotective Activity of Elettaria cardamomum (Cardamom) and Foeniculum vulgare (Fennel) in H2O2-Induced Oxidative Stress in SH-SY5Y Cells and Acellular Assays. · Pharmaceuticals (Basel, Switzerland)
8.PMID: 31430531 (2020) — Antibacterial and anti-inflammatory activities of cardamom (Elettaria cardamomum) extracts: Potential therapeutic benefits for periodontal infections. · Anaerobe
9.PMID: 37235027 (2023) — Small cardamom genome: development and utilization of microsatellite markers from a draft genome sequence of Elettaria cardamomum Maton. · Frontiers in plant science
10.PMID: 27888503 (2017) — Anti-hypercholesterolemic influence of the spice cardamom (Elettaria cardamomum) in experimental rats. · Journal of the science of food and agriculture
11.PMID: 34579443 (2021) — Benefits of Cardamom (Elettaria cardamomum (L.) Maton) and Turmeric (Curcuma longa L.) Extracts for Their Applications as Natural Anti-Inflammatory Adjuvants. · Plants (Basel, Switzerland)
12.PMID: 31541721 (2020) — Botany, traditional uses, phytochemistry and biological activities of cardamom [Elettaria cardamomum (L.) Maton] - A critical review. · Journal of ethnopharmacology
13.PMID: 29214141 (2017) — New trends in anaphylaxis. · Allergo journal international
14.PMID: 7039980 (1982) — Cardamom--production, technology, chemistry, and quality. · Critical reviews in food science and nutrition
15.PMID: 23795480 (2013) — [Water-soluble glucans from true cardamom (Elettaria cardamomum White at Maton) seeds]. · Prikladnaia biokhimiia i mikrobiologiia
16.PMID: 39334932 (2024) — Deciphering the Potentials of Cardamom in Cancer Prevention and Therapy: From Kitchen to Clinic. · Biomolecules
17.PMID: 37447289 (2023) — Protective Role of Phenolic Compounds from Whole Cardamom (Elettaria cardamomum (L.) Maton) against LPS-Induced Inflammation in Colon and Macrophage Cells. · Nutrients
18.PMID: 28070488 (2017) — Transcriptome profiling of Elettaria cardamomum (L.) Maton (small cardamom). · Genomics data
19.PMID: 32626343 (2019) — Safety and efficacy of an essential oil from Elettaria cardamomum (L.) Maton when used as a sensory additive in feed for all animal species. · EFSA journal. European Food Safety Authority
20.PMID: 35684370 (2022) — Effect of the Instant Controlled Pressure Drop Technology in Cardamom (Elettaria cardamomum) Essential Oil Extraction and Antioxidant Activity. · Molecules (Basel, Switzerland)
21.PMID: 28073098 (2017) — The effect of Elettaria cardamomum extract on anxiety-like behavior in a rat model of post-traumatic stress disorder. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
22.PMID: 35684260 (2022) — Chemical Profile, Antibacterial and Antioxidant Potential of Zingiber officinale Roscoe and Elettaria cardamomum (L.) Maton Essential Oils and Extracts. · Plants (Basel, Switzerland)
23.PMID: 26161806 (2015) — Assessment of hormone-like activities in Ginkgo biloba, Elettaria cardamomum and Plantago ovata extracts using in vitro receptor-specific bioassays. · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
24.PMID: 16298093 (2006) — Gastroprotective effect of cardamom, Elettaria cardamomum Maton. fruits in rats. · Journal of ethnopharmacology