Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Phyto-extracts of C. sativa in cream formulations may serve as cosmeceuticals to protect skin against the injurious effects of UV radiation [PMID:26448818]
Dietary supplementation at 1.1% in FVB/n mice reduced abdominal adipose tissue and lowered serum cholesterol [PMID:32260459]
Bark extract reduced ROS formation and improved cell viability in neonatal rat cardiomyocytes; it also induced transient negative chronotropic and positive inotropic effects in guinea pig atria [PMID:23533692]
Bark extract demonstrated antimutagenic properties against mitomycin C and vinblastine in TK6 cells, and heartwood triterpenoids showed cytotoxicity against breast (MCF-7) and prostate (PC3) cancer cell lines [PMID:37896225, PMID:28363853]
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 26448818 (2015) — Anti-Aging Potential of Phytoextract Loaded-Pharmaceutical Creams for Human Skin Cell Longetivity. · Oxidative medicine and cellular longevity
- 2.PMID: 36553794 (2022) — Sweet Chestnut (Castanea sativa Mill.) Nutritional and Phenolic Composition Interactions with Chestnut Flavor Physiology. · Foods (Basel, Switzerland)
- 3.PMID: 25204784 (2015) — Castanea sativa by-products: a review on added value and sustainable application. · Natural product research
- 4.PMID: 36615589 (2023) — Tannins-Based Extracts: Effects on Gut Chicken Spontaneous Contractility. · Molecules (Basel, Switzerland)
- 5.PMID: 28363853 (2017) — Cytotoxic triterpenoids isolated from sweet chestnut heartwood (Castanea sativa) and their health benefits implication. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association