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CC
Not CommonRésumée par IA
Cinnamomum Camphora
Cinnamomum camphora
soulagement local de la douleur dans la médecine populaire japonaise
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Cinnamomum camphora is an economically and medicinally important tree species valued for its essential oils, which exhibit a wide range of biological activities including anti-inflammatory, antimicrobial, and anti-tumor effects [PMID:35566046, PMID:42197601, PMID:41168689].
Contexte
Cinnamomum camphora, also known as the camphor tree or Camphora officinarum, is an ornamental evergreen broadleaved tree dominant in subtropical urban landscapes [PMID:35566046, PMID:37697363, PMID:42197601]. It is widely cultivated for its timber and the production of camphor and essential oils [PMID:35566046, PMID:42197601].
Usages traditionnels
Historically, the plant and its products have been used as a fumigant during the Black Death, as an ingredient in embalming fluids and perfumes, and as a treatment for inflammation, infection, congestion, muscle pain, and irritation [PMID:35566046, PMID:23666009]. It is also used in traditional medicine and as a topical analgesic and rubefacient for minor muscle aches [PMID:23666009, PMID:38101618].
Composés actifs
The plant produces essential oils rich in monoterpenes and sesquiterpenes [PMID:41168689]. Major constituents vary by chemotype and include 1,8-cineole (eucalyptol), camphor, linalool, borneol, sabinene, alpha-terpineol, neral, and geranial [PMID:37533252, PMID:36364183, PMID:36589079, PMID:42029632]. Other non-volatile constituents include flavonoids, lignans, and phenolic compounds [PMID:42197601, PMID:42123912].
Mécanisme d'action
Cinnamomum camphora essential oil (CCEO) exhibits anti-tumor activity in breast cancer by modulating NADPH oxidase 4 (NOX4) via (+)-2-bornanone [PMID:41016298]. L-borneol promotes skin wound healing by regulating the rno-miR-127/PODXL2 axis to stimulate the differentiation of hair follicle stem cells into basal layer cells [PMID:40378434]. The essential oil also demonstrates anti-virulence activity by inhibiting quorum sensing, reducing bacterial motility, and suppressing biofilm formation [PMID:42029632].
Preuves cliniques
Preuve DBreast Cancer
CCEO exhibited significant anti-tumor activity both in vitro and in vivo via NOX4 modulation [PMID:41016298]
Preuve DSkin Wounds
L-borneol promotes the differentiation of hair follicle stem cells into epidermal cells to facilitate wound repair [PMID:40378434]
Preuve DBacterial Infections
Essential oil showed significant antimicrobial activity against E. coli, S. aureus, and P. aeruginosa [PMID:42029632]
Preuve DAcne
C. camphora is part of the multi-herbal formula Yuqingyan, which has demonstrated potential for acne treatment [PMID:41349703]
Sécurité et effets indésirables
The safety profile of Cinnamomum camphora chvar. borneol essential oil remains poorly characterized [PMID:39041145].
Synthèse des preuves
The current evidence is primarily based on in vitro studies, animal models (xenografts, rats), and literature reviews, indicating a low to moderate overall strength of clinical evidence (Level C/D).
Sources PubMed
1.PMID: 35566046 (2022) — Phytochemistry and Applications of Cinnamomum camphora Essential Oils. · Molecules (Basel, Switzerland)
3.PMID: 38101618 (2024) — Adjusting function of camphor on primary metabolism in Cinnamomum camphora stressed by high temperature. · Plant science : an international journal of experimental plant biology
4.PMID: 37004435 (2023) — Thermal protection function of camphor on Cinnamomum camphora cell membrane by acting as a signaling molecule. · Plant physiology and biochemistry : PPB
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
— The Odorant Receptor Recognizing Camphor in a Camphor Tree Specialist Orthaga achatina (Lepidoptera: Pyralidae).
· Journal of agricultural and food chemistry
6.PMID: 37533252 (2023) — Comparative Chemical Composition and Acetylcholinesterase (AChE) Inhibitory Potential of Cinnamomum camphora and Cinnamomum tamala. · Chemistry & biodiversity
7.PMID: 37697363 (2023) — Genome and whole-genome resequencing of Cinnamomum camphora elucidate its dominance in subtropical urban landscapes. · BMC biology
8.PMID: 41168689 (2025) — Genome-wide identification and characterization of the AP2/ERF gene family in Cinnamomum camphora. · BMC genomics
9.PMID: 41349703 (2026) — Anti-acne mechanisms of Yuqingyan, a novel multi-herbal formula derived from traditional Chinese medicine. · Journal of ethnopharmacology
10.PMID: 41016298 (2025) — Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone. · Phytomedicine : international journal of phytotherapy and phytopharmacology
11.PMID: 36364183 (2022) — Chemical Composition and Antioxidant Activity of the Essential Oils of Citral-Rich Chemotype Cinnamomum camphora and Cinnamomum bodinieri. · Molecules (Basel, Switzerland)
12.PMID: 39041145 (2024) — [Chemical composition and pharmacological effects of Cinnamomum camphora chvar. borneol essential oil: a review]. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
13.PMID: 42280789 (2026) — Correlative Changes in Endogenous Polyamines and Hormones Associated with Aging in Ancient Cinnamomum camphora. · Plants (Basel, Switzerland)
15.PMID: 36589079 (2022) — The uppermost monoterpenes improving Cinnamomum camphora thermotolerance by serving signaling functions. · Frontiers in plant science
16.PMID: 40378434 (2025) — L-borneol regulates rno-miR-127/ PODXL2 to promote hair follicle stem cells to repair skin wounds. · International immunopharmacology
17.PMID: 34371571 (2021) — Chemical Composition and Nematicidal Properties of Sixteen Essential Oils-A Review. · Plants (Basel, Switzerland)
18.PMID: 36080152 (2022) — Extraction of Camphor Tree Essential Oil by Steam Distillation and Supercritical CO2 Extraction. · Molecules (Basel, Switzerland)
19.PMID: 36479586 (2022) — Chromosome-level genome assembly and resequencing of camphor tree (Cinnamomum camphora) provides insight into phylogeny and diversification of terpenoid and triglyceride biosynthesis of Cinnamomum. · Horticulture research
20.PMID: 23666009 (2013) — Camphor--a fumigant during the Black Death and a coveted fragrant wood in ancient Egypt and Babylon--a review. · Molecules (Basel, Switzerland)
21.PMID: 36770639 (2023) — Chemical Variation and Environmental Influence on Essential Oil of Cinnamomum camphora. · Molecules (Basel, Switzerland)
22.PMID: 42029632 (2026) — GC-MS Analysis, Biological Characterization, Quorum Sensing Inhibition, and Molecular Docking of Cinnamomum camphora L. · Chemistry & biodiversity