Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Lipidic extracts and ointments (2.5% and 5%) showed wound-healing activity in rat and mice models [PMID:37866421, 31143772]. A combination ointment with Marrubium vulgare accelerated burn wound healing and showed analgesic and anti-inflammatory effects [PMID:35337087].
Methanolic extracts showed promising cytotoxic activity against human breast cancer cell lines MCF-7 and MDA-MB-468 without cytotoxicity toward normal PBMCs [PMID:35408507]. Other studies noted antiproliferative and cytotoxic properties [PMID:39599445, 34015367].
Extracts demonstrated antibacterial activity against Proteus mirabilis, Bacillus subtilis, Staphylococcus aureus, and Escherichia coli, as well as antifungal activity against Candida species and Alternaria alternata [PMID:35408507, 37866421, 37372075, 28665341].
A specific root extract fraction ('K') reduced immobility time in the forced swim test in a mouse model, showing effects comparable to paroxetine [PMID:35256610].
Methanolic extracts showed potent in vitro inhibitory activity against α-amylase and α-glucosidase and an antiglycation effect [PMID:35408507].
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 21754752 (2011) — 3-(4-Chloro-phen-yl)-1-[(2R,4aR,8aR)-4a,8-dimethyl-1,2,3,4,4a,5,6,8a-octa-hydro-naphthalen-2-yl]prop-2-en-1-one. · Acta crystallographica. Section E, Structure reports online
- 2.PMID: 21754232 (2011) — 1-(4a,8-Dimethyl-1,2,3,4,4a,5,6,8a-octa-hydro-naphthalen-2-yl)-3-phenyl-prop-2-en-1-one. · Acta crystallographica. Section E, Structure reports online
- 3.PMID: 21522737 (2010) — 3-[4-(Dimethyl-amino)-phen-yl]-1-(4a,8-dimethyl-1,2,3,4,4a,5,6,8a-octa-hydro-naphthalen-2-yl)prop-2-en-1-one. · Acta crystallographica. Section E, Structure reports online
- 4.PMID: 22904849 (2012) — Methyl 2-(4a,8-Dimethyl-7-oxodeca-hydro-naphthalen-2-yl)acrylate. · Acta crystallographica. Section E, Structure reports online
- 5.PMID: 22259450