Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Stem bark extract suppressed lipopolysaccharide-induced inflammation in RAW 264.7 macrophages [PMID:23796875]; leaf extracts showed strong to medium anti-inflammatory activity in vitro [PMID:35847017].
Hydro-ethanolic stem bark extract demonstrated protective roles against acetaminophen-induced and carbon tetrachloride-induced hepatotoxicity [PMID:40714060, PMID:32904230].
Root extracts (specifically apigenin and robinetin) reduced capillary formation in chick chorioallantoic membranes [PMID:25482106].
Stem bark hydroalcoholic extract showed neuroprotective potential against sodium fluoride-induced biochemical and behavioral alterations in mice and rats [PMID:41747847].
Computational analysis suggests potential for identified compounds to act as ligands for glucokinase stimulation [PMID:37570723].
Synthèse des preuves
Sources PubMed
- 1.PMID: 31517111 (2019) — The phytochemical and pharmacological actions of Entada africana Guill. & Perr. · Heliyon
- 2.PMID: 25482106 (2015) — Anti-angiogenic activity of Entada africana root. · Natural product research
- 3.PMID: 40714060 (2025) — Enzyme kinetic and in silico characterization of cytochrome P450 2E1 inhibition by hydro-ethanolic extract of Entada africana and its protective role in acetaminophen-induced hepatotoxicity. · Journal of ethnopharmacology
- 4.PMID: 37570723 (2023) — Profiling the Antidiabetic Potential of Compounds Identified from Fractionated Extracts of Entada africana toward Glucokinase Stimulation: Computational Insight. · Molecules (Basel, Switzerland)
- 5.PMID: 23796875 (2013)