Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Finger root (Boesenbergia rotunda) contains bioactive flavonoids, particularly panduratin A, pinostrobin, and pinocembrin, which demonstrate antimicrobial activity against various bacteria and fungi. These compounds appear to disrupt microbial cell membranes and inhibit bacterial growth. Research suggests panduratin A shows particularly strong activity against oral pathogens. Evidence level: C (preliminary clinical evidence).
Does finger root interact with any medications?
There is limited clinical data on finger root drug interactions. No significant interactions have been documented in traditional use, where it is commonly consumed as a culinary spice. However, due to limited research, individuals taking prescription medications should consult a healthcare provider before using concentrated finger root supplements. Evidence level: C (traditional use and preliminary studies).
What is the recommended daily dosage of finger root?
The traditional adult dosage for finger root rhizome is 3-6 grams daily. This can be consumed as a tea, decoction, or added to food. For standardized extracts, follow manufacturer guidelines as concentrations vary. There is insufficient clinical trial data to establish evidence-based therapeutic dosing. Evidence level: C (traditional use).
Is finger root safe to use during pregnancy?
Finger root is considered safe when consumed in normal culinary amounts during pregnancy. However, medicinal or concentrated doses should be avoided during pregnancy as a precaution. In Indonesian Jamu tradition, finger root is specifically used during post-partum care to support recovery, indicating its traditional safety profile for new mothers. Evidence level: Traditional.
What is finger root used for in traditional medicine?
Finger root is used in Thai and Indonesian traditional medicine primarily for digestive complaints, oral health, and women's health conditions. In Thai medicine, it addresses digestive issues, while Indonesian Jamu uses it for mouth infections and post-partum recovery. The rhizome's antimicrobial properties make it valuable for oral health applications. Evidence level: C (traditional use with preliminary research).
Are there any side effects from taking finger root?
Finger root is generally well tolerated with no serious adverse effects reported in traditional use. As a common culinary ingredient in Southeast Asian cuisine, it has a long history of safe consumption. Mild gastrointestinal discomfort may occur in sensitive individuals at higher doses. No serious toxicity has been documented. Evidence level: C (traditional use and preliminary studies).
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Boesenbergia rotunda, known as fingerroot, is a Southeast Asian medicinal plant and food ingredient with reported anti-inflammatory, antioxidant, and anticancer properties [PMID:28503050, PMID:40176912].
Contexte
Boesenbergia rotunda (Family: Zingiberaceae), also known as fingerroot or Chinese ginger, is a medicinal and food plant widely distributed in southern China, Southeast Asia, and South Asia [PMID:28503050, PMID:40176912].
Usages traditionnels
It is used as a spice and traditional herb for beneficial effects on Qi, appetite, stagnation, and pain relief [PMID:40176912]. In the Thailand primary health care system, the rhizome is recommended for treating stomachache, leukoplakia, abscesses, and leukorrhea [PMID:32730867].
Composés actifs
Common phytochemical components include alkaloids, essential oils, flavonoids, and phenolics [PMID:28503050]. Key bioactive compounds include boesenbergin, krachaizin, pinostrobin, pinocembrin, cardamonin, and the chalcone derivative panduratin A [PMID:28503050, PMID:35306173, PMID:32270712, PMID:36106139].
Mécanisme d'action
Mechanisms include the activation of autophagy through AMPK activation [PMID:41001742], induction of caspase-dependent apoptosis (caspase-8 and caspase-3) and G2/M-phase arrest in cancer cells [PMID:32270712], and vasorelaxation via endothelium-dependent NO-cGMP pathways [PMID:33271853]. It may also inhibit DNA topoisomerase I [PMID:11321439] and suppress adipogenesis by reducing levels of C/EBPα, PPARγ, and SREBP-1c [PMID:36230099].
Preuves cliniques
Preuve CGingival inflammation/Periodontitis
Standardized extracts show promising utility via direct antimicrobial effects against Porphyromonas gingivalis and anti-inflammatory actions [PMID:35306173]
Preuve DDiabetic Nephropathy and Cardiomyopathy (Rats)
Ethyl acetate fraction mitigated these conditions by regulating oxidative inflammatory pathways [PMID:40956519]
Preuve DDoxorubicin-induced Cardiotoxicity (Rats)
Extract attenuated cardiac weight loss and injury by reducing oxidative stress and increasing glutathione, SOD, and catalase [PMID:37452121]
Preuve DCisplatin-induced Nephrotoxicity (Rats)
Ethanol extract reduced blood levels of creatinine, urea nitrogen, and malondialdehyde [PMID:38736464]
Preuve DSexual Behaviour (Rats)
Sécurité et effets indésirables
A 90-day oral administration of a cyclodextrin-formulated extract (containing panduratin A and pinostrobin) in Wistar rats was evaluated for sub-chronic toxicity [PMID:38328737].
Synthèse des preuves
The majority of evidence is based on in vitro studies and animal models (Level D) or literature reviews (Level C). There are no human clinical trials (Level B) or meta-analyses (Level A) provided in the source abstracts.
Sources PubMed
1.PMID: 28503050 (2017) — Fingerroot, Boesenbergia rotunda and its Aphrodisiac Activity. · Pharmacognosy reviews
2.PMID: 35306173 (2022) — Toward the use of Boesenbergia rotunda extracts and the chalcone panduratin A to treat periodontitis. · Journal of oral biosciences
3.PMID: 40362555 (2025) — Potential Cutaneous Applications of Boesenbergia rotunda Extract Based on Its In Vitro Anti-Melanogenic and Anti-Fibroproliferative Properties. · International journal of molecular sciences
4.PMID: 32270712 (2021) — Cytotoxic Activity of Boesenbergia rotunda Extracts against Nasopharyngeal Carcinoma Cells (HK1). Cardamonin, a Boesenbergia rotunda Constituent, Inhibits Growth and Migration of HK1 Cells by Inducing Caspase-Dependent Apoptosis and G2/M-Phase Arrest. · Nutrition and cancer
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
Ethanolic extract administration for 60 days showed no significant difference in courtship behaviour, mount frequency, or intromission frequency [PMID:17968473]
Preuve DCancer (In Vitro)
Cardamonin inhibits growth and migration of nasopharyngeal carcinoma cells [PMID:32270712]; pinostrobin exhibits anticancer activity against breast cancer cells [PMID:40383961, PMID:36106139]
Preuve DSkin Hyperpigmentation (In Vitro)
Extract and panduratin A reduced tyrosinase activity and cellular melanogenesis induced by UVA radiation [PMID:40362555]
— Effects of Boesenbergia rotunda (L.) Mansf. on sexual behaviour of male rats.
· Asian journal of andrology
6.PMID: 36106139 (2022) — A Potential Anticancer Mechanism of Finger Root (Boesenbergia rotunda) Extracts against a Breast Cancer Cell Line. · Scientifica
7.PMID: 40956519 (2025) — Chinese ginger (Boesenbergia rotunda) mitigates diabetic nephropathy and cardiomyopathy by regulating oxidative inflammatory pathway. · Journal of molecular histology
8.PMID: 38328737 (2024) — Oral sub-chronic toxicity of fingerroot (Boesenbergia rotunda) rhizome extract formulation in Wistar rats. · Toxicology reports
9.PMID: 35356266 (2022) — Anti-Inflammatory and Antinociceptive Effects of Boesenbergia rotunda Polyphenol Extract in Diabetic Peripheral Neuropathic Rats. · Journal of pain research
10.PMID: 36855350 (2023) — Antiprotozoal activity of Boesenbergia rotunda (L.) Mansf and Ganoderma lucidum (Fr.) Kart extracts against Blastocystis hominis. · Veterinary world
11.PMID: 40176912 (2025) — Traditional usages, chemical metabolites, pharmacological activities, and pharmacokinetics of Boesenbergia rotunda (L.) Mansf.: a comprehensive review. · Frontiers in pharmacology
12.PMID: 32730867 (2020) — Boesenbergia rotunda extract inhibits Candida albicans biofilm formation by pinostrobin and pinocembrin. · Journal of ethnopharmacology
13.PMID: 33271853 (2020) — Vasorelaxant Effect of Boesenbergia rotunda and Its Active Ingredients on an Isolated Coronary Artery. · Plants (Basel, Switzerland)
14.PMID: 40383961 (2025) — Anticancer Effect of Pinostrobin on Human Breast Cancer Cells Through Regulation of Epithelial Mesenchymal Transition. · Integrative cancer therapies
15.PMID: 36230099 (2022) — Pinostrobin: An Adipogenic Suppressor from Fingerroot (Boesenbergia rotunda) and Its Possible Mechanisms. · Foods (Basel, Switzerland)
16.PMID: 41001742 (2025) — Panduratin A Induces Autophagy Through AMPK Activation Independent of mTOR Inhibition and Restricts Mycobacterium tuberculosis in Host Macrophages. · Molecular microbiology
17.PMID: 40650064 (2025) — Pharmacological Evaluation of a Traditional Thai Polyherbal Formula for Alzheimer's Disease: Evidence from In Vitro and In Silico Studies. · International journal of molecular sciences
18.PMID: 37452121 (2023) — Boesenbergia rotunda displayed anti-inflammatory, antioxidant and anti-apoptotic efficacy in doxorubicin-induced cardiotoxicity in rats. · Scientific reports
19.PMID: 38736464 (2024) — The Nephroprotective Activity of Boesenbergia Rotunda Rhizome by Reducing Creatinine, Urea Nitrogen, Glutamic Pyruvic Transaminase, and Malondialdehyde Levels in the Blood and Attenuating the Expression of Havcr1 (KIM-1), Lcn2 (NGAL), Casp3, and Casp7 Genes in the Kidney Cortex of Cisplatin-Induced Sprague-Dawley Rats. · Journal of experimental pharmacology
20.PMID: 38414781 (2024) — Physicochemical and biological properties of encapsulated Boesenbergia rotunda extract with different wall materials in enhancing antioxidant, mineralogenic and osteogenic activities of MC3T3-E1 cells. · Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
21.PMID: 11321439 (2000) — Cytotoxic mechanism of flavonoid from Temu Kunci (Kaempferia pandurata) in cell culture of human mammary carcinoma. · Clinical hemorheology and microcirculation
22.PMID: 31944087 (2020) — Determination of Quercetin and Flavonol Synthase in Boesenbergia rotunda Rhizome. · Pakistan journal of biological sciences : PJBS