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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Fortunella japonica (kumquat) is a small citrus fruit whose extracts and essential oils demonstrate antioxidant, anti-inflammatory, and antimicrobial properties [PMID:40407011, PMID:29976894, PMID:20350876].
Contexte
Fortunella japonica, also known as kumquat or Citrus japonica, is a member of the Rutaceae family [PMID:39593961, PMID:34783965]. It is widely cultivated and consumed as fresh fruit and used in traditional medicine, particularly in China [PMID:27243926].
Usages traditionnels
In China, the fruits are used in traditional medicine [PMID:27243926]. Additionally, citrus peel (referred to as 'Jin-Pi') is used in traditional medicine for digestion, severe cold, and fever [PMID:20350876].
Composés actifs
The fruit contains polyphenols, including quinic acid, p-hydroxybenzoic acid [PMID:40407011], and flavonoids such as 3',5'-di-C-glucopyranosylphloretin, margaritene, isomargaritene, fortunellin, apigenin 8-C-neohesperidoside, poncirin, and rhoifolin [PMID:25308680, PMID:27243926]. The essential oil is predominantly composed of limonene [PMID:15740053, PMID:26500054], with other components including myrcene, ethyl acetate, camphene, terpinen-4-ol, citronellyl formate, and citronellyl acetate [PMID:15740053].
Mécanisme d'action
Kumquat polyphenols may enhance cognitive memory by reducing oxidative stress, lowering inflammatory markers, and decreasing acetylcholinesterase activity in the hippocampus, while increasing acetylcholine levels via modulation of the p53/SIRT1/NF-κB pathway [PMID:40407011]. Kumquat essential oil has been shown to decrease proliferation and activate JNK signaling and apoptosis (via PARP cleavage) in HT-1080 fibrosarcoma cells [PMID:34783965].
Preuves cliniques
Preuve DCognitive memory function (aging model)
Administration of whole fruit free phenols (50-200 mg/kg/day) in D-galactose-induced senescence mice reduced oxidative stress and enhanced cognitive memory [PMID:40407011]
Preuve DFibrosarcoma (HT-1080 cells)
Kumquat essential oil decreased cell proliferation and viability and stimulated apoptosis via JNK signaling [PMID:34783965]
Preuve DSkin pathogens
Essential oils of F. japonica var. margarita exhibited strong antimicrobial activity against Staphylococcus epidermidis, Propionibacterium acnes, Malassezia furfur, and Candida albicans [PMID:20350876]
Preuve DDiabetic foot ulcer pathogens
Pulp non-polar extracts showed weak to moderate efficacy against Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans [PMID:42243229]
Sécurité et effets indésirables
A case of anaphylaxis to kumquat (Citrus japonica) has been reported [PMID:39589041].
Synthèse des preuves
The current evidence is primarily based on in vitro cell line studies, animal models (mice), and individual case reports, indicating a low overall strength of clinical evidence for human use.
Sources PubMed
1.PMID: 29976894 (2018) — Biological Activities and Safety of Citrus spp. Essential Oils. · International journal of molecular sciences
2.PMID: 40407011 (2025) — Enhancing cognitive memory function with kumquat (Fortunella japonica Swingle) polyphenol extract: mechanisms of action in D-galactose-induced aging model mice. · Food & function
3.PMID: 39589041 (2024) — A case of anaphylaxis to kumquat (Citrus japonica). · European journal of dermatology : EJD
4.PMID: 39593961 (2024) — Chemical Profile of Kumquat (Citrus japonica var. margarita) Essential Oil, In Vitro Digestion, and Biological Activity. · Foods (Basel, Switzerland)
5.PMID: 34783965 (2022) — Kumquat essential oil decreases proliferation and activates JNK signaling and apoptosis in HT-1080 fibrosarcoma cells.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 20350876 (2010) — Inhibitory effects of Fortunella japonica var. margarita and Citrus sunki essential oils on nitric oxide production and skin pathogens. · Acta microbiologica et immunologica Hungarica
7.PMID: 15740053 (2005) — Characteristic odor components of kumquat (Fortunella japonica Swingle) peel oil. · Journal of agricultural and food chemistry
8.PMID: 27243926 (2016) — Chemical Profiling Using Uplc Q-Tof/Ms and Antioxidant Activities of Fortunella Fruits. · Journal of food science
9.PMID: 42243229 (2026) — Molecular networking-based GC/MS profiling of Citrus japonica Thunb. peel and pulp lipophilic fractions and their antimicrobial potential against diabetic foot ulcer pathogens. · Scientific reports
10.PMID: 25308680 (2015) — Drying effect on flavonoid composition and antioxidant activity of immature kumquat. · Food chemistry
11.PMID: 26500054 (2016) — Chemical constituents and antioxidant activity of essential oil and organic extract from the peel and kernel parts of Citrus japonica Thunb. (kumquat) from Iran. · Natural product research