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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Eight-herb Rehmannia formula
Classical Kampo/TCM formula with eight herbs centered on prepared Rehmannia; used for kidney yang deficiency — one of the most prescribed Kampo formulas.
Hachimijiogan is a classical Kampo formula comprising eight herbs, with prepared Rehmannia as the principal component, traditionally used for kidney yang deficiency and among the most prescribed Kampo formulas in Japan. Modern research explores its applications in diabetes, renal protection, and anti-aging. Key active compounds include catalpol, rehmannioside, loganin, alisol, and paeoniflorin.
Hachimijiogan exhibits multifaceted pharmacological actions, including modulation of the hypothalamic-pituitary-adrenal axis and enhancement of renal function via compounds like catalpol and paeoniflorin. It improves glucose metabolism through activation of AMPK and PPARγ pathways, and exerts anti-inflammatory effects by inhibiting NF-κB signaling. The formula also demonstrates antioxidant properties via upregulation of Nrf2 and reduction of oxidative stress markers.
Classical Kampo/TCM formula with eight herbs centered on prepared Rehmannia; used for kidney yang deficiency — one of the most prescribed Kampo formulas.
Hachimijiogan is a classical Kampo formula comprising eight herbs, with prepared Rehmannia as the principal component, traditionally used for kidney yang deficiency and among the most prescribed Kampo formulas in Japan. Modern research explores its applications in diabetes, renal protection, and anti-aging. Key active compounds include catalpol, rehmannioside, loganin, alisol, and paeoniflorin.
Hachimijiogan exhibits multifaceted pharmacological actions, including modulation of the hypothalamic-pituitary-adrenal axis and enhancement of renal function via compounds like catalpol and paeoniflorin. It improves glucose metabolism through activation of AMPK and PPARγ pathways, and exerts anti-inflammatory effects by inhibiting NF-κB signaling. The formula also demonstrates antioxidant properties via upregulation of Nrf2 and reduction of oxidative stress markers.