Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Impatiens balsamina is an annual herb of the Balsaminaceae family used in folk medicine for various inflammatory and pain conditions [PMID:36436713].
Contexte
Impatiens balsamina is an annual herbaceous plant cultivated extensively in Asia and other tropical and subtropical regions as an ornamental plant [PMID:36436713, PMID:39561440].
Usages traditionnels
It has been long prescribed in folk medicine for the treatment of rheumatism, isthmus, generalized pain, fractures, inflammation of the nails, scurvy, carbuncles, dysentery, bruises, and foot diseases [PMID:36436713]. In traditional Chinese and Thai medicine, it is used for hair loss and various skin conditions [PMID:39561440].
Composés actifs
Over 307 natural compounds have been identified, including flavonoids, naphthoquinones (such as 2-methoxy-1,4-naphthoquinone), coumarins, and terpenoids [PMID:36436713, PMID:21754213, PMID:39561440]. Other identified compounds include biflavonoid glycosides (balsamisides A-D), oleanane-type triterpenoidal glycosides (imbalosides A-C), baccharane glycosides (hosenkosides L-O), and Ib-AMP antimicrobial peptides [PMID:28165740, PMID:32846890, PMID:7765763, PMID:37185763].
Mécanisme d'action
The plant may exert anti-androgenic effects through the inhibition of steroid 5-alpha reductase (S5αR) [PMID:39561440]. Certain seed and callus extracts demonstrate antioxidant activities and lipid accumulation-inhibitory effects [PMID:42280753].
Preuves cliniques
Preuve DAndrogenetic alopecia
Topical application of Impatiens balsamina was capable of promoting new hair growth in the dorsal skin lesions of a mouse model [PMID:31852654]
Sécurité et effets indésirables
Toxicity evaluations of extracts and isolated biomarkers on skin cells, keratinocytes, and fibroblasts were performed, though specific adverse results were not detailed in the provided abstract [PMID:39561440].
Synthèse des preuves
The current evidence is primarily based on phytochemical screening, in vitro assays, and animal models (Level D), with a comprehensive review of ethnobotanical uses (Level C). No human clinical trials were provided.
Sources PubMed
- 1.PMID: 21754213 (2011) — 2-Meth-oxy-naphthalene-1,4-dione. · Acta crystallographica. Section E, Structure reports online
- 2.PMID: 36436713 (2023) — Impatiens balsamina: An updated review on the ethnobotanical uses, phytochemistry, and pharmacological activity. · Journal of ethnopharmacology
- 3.PMID: 28165740 (2017) — Anti-Neurodegenerative Biflavonoid Glycosides from Impatiens balsamina. · Journal of natural products
- 4.PMID: 37185763 (2023) — Plant Antimicrobial Peptides: Insights into Structure-Function Relationships for Practical Applications. · Current issues in molecular biology
- 5.PMID: 42280753 (2026) — Antioxidant Activities and Lipid Accumulation-Inhibitory Effects of Seed and Callus Extracts of Impatiens balsamina L.