Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 26 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Leaf extracts significantly reduced parasitemia and protected the spleen, liver, and lungs from tissue injury and oxidative stress [PMID:26109255, 29630927, 40917784].
Leaf extract mitigated lead-acetate-induced damage and apoptosis in the kidneys, brain, liver, and testes [PMID:27330278, 28123424, 27391413, 27052307].
Leaf extract decreased parasitemia by 70%, reduced weight loss, and mitigated spleen and liver injury [PMID:30898472, 32346351].
Leaf extracts and isolated peptides showed antimicrobial activity against various Gram-positive and Gram-negative bacteria and yeasts such as Candida albicans [PMID:32210676, 11167035, 10363845].
Treatment significantly increased antioxidant status and reduced serum marker enzymes (ALT, AST, ALP, LDH) [PMID:16117622].
Synthèse des preuves
Sources PubMed
- 1.PMID: 29062263 (2017) — Indigofera oblongifolia leaf extract regulates spleen macrophage response during Plasmodium chabaudi infection. · Saudi journal of biological sciences
- 2.PMID: 32210676 (2020) — Anthelmintic and antimicrobial activity of Indigofera oblongifolia leaf extracts. · Saudi journal of biological sciences
- 3.PMID: 27330278 (2016) — Indigofera oblongifolia mitigates lead-acetate-induced kidney damage and apoptosis in a rat model. · Drug design, development and therapy
- 4.PMID: 40917784 (2025) — Morphometric analysis and immunobiological investigation of Indigofera oblongifolia on the infected lung with Plasmodium chabaudi. · Open life sciences
- 5.PMID: 28123424 (2016)