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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Celastrus paniculatus
A climbing shrub whose seeds yield an oil used in Ayurveda as a potent brain tonic and for intellectual enhancement.
Celastrus paniculatus, known as Intellect Tree, is a climbing shrub whose seeds yield an oil traditionally used in Ayurveda as a potent brain tonic for intellectual enhancement. Modern research suggests it possesses nootropic, neuroprotective, and anxiolytic properties, attributed to active compounds such as celastrine, paniculatine, and malkangunin. Its evidence level is C, indicating limited clinical studies supporting its cognitive benefits.
The nootropic effects of Celastrus paniculatus are primarily mediated through acetylcholinesterase inhibition, which increases acetylcholine availability in the brain, enhancing memory and learning. Additionally, its antioxidant and anti-inflammatory actions, via modulation of NF-κB and Nrf2 pathways, protect neurons from oxidative stress. The alkaloids celastrine and paniculatine may also interact with serotonin and dopamine receptors, contributing to anxiolytic and mood-stabilizing effects. Furthermore, the oil promotes neurotrophic factors like BDNF, supporting synaptic plasticity.
A climbing shrub whose seeds yield an oil used in Ayurveda as a potent brain tonic and for intellectual enhancement.
Celastrus paniculatus, known as Intellect Tree, is a climbing shrub whose seeds yield an oil traditionally used in Ayurveda as a potent brain tonic for intellectual enhancement. Modern research suggests it possesses nootropic, neuroprotective, and anxiolytic properties, attributed to active compounds such as celastrine, paniculatine, and malkangunin. Its evidence level is C, indicating limited clinical studies supporting its cognitive benefits.
The nootropic effects of Celastrus paniculatus are primarily mediated through acetylcholinesterase inhibition, which increases acetylcholine availability in the brain, enhancing memory and learning. Additionally, its antioxidant and anti-inflammatory actions, via modulation of NF-κB and Nrf2 pathways, protect neurons from oxidative stress. The alkaloids celastrine and paniculatine may also interact with serotonin and dopamine receptors, contributing to anxiolytic and mood-stabilizing effects. Furthermore, the oil promotes neurotrophic factors like BDNF, supporting synaptic plasticity.