Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
A single-blind, placebo-controlled study of 40 patients showed efficacy in reducing blood pressure using 3g of N. jatamansi daily for 4 weeks [PMID:33066862].
In vitro and in vivo models (Drosophila) suggest neuroprotective effects against Aβ42-induced toxicity and Tau-induced neurotoxicity, improving lifespan and memory [PMID:35247505, PMID:35864434, PMID:29398668].
Extracts and nardosinone demonstrated neuroprotective effects by modulating T cell infiltration and suppressing glucose metabolic reprogramming in mouse models [PMID:40358168, PMID:35178995].
Experimental animal studies (rats and mice) indicate central nervous system depressant activity [PMID:35813358].
Aromatherapy with N. jatamansi essential oil was evaluated for mitigating sleep deprivation-induced myocardial injury by targeting the MAOA gene [PMID:40364704].
Synthèse des preuves
Sources PubMed
- 1.PMID: 38042505 (2024) — Nardostachys jatamansi: Phytochemistry, ethnomedicinal uses, and pharmacological activities: A comprehensive review. · Fitoterapia
- 2.PMID: 31775790 (2019) — Medicinal plants of the Bible-revisited. · Journal of ethnobiology and ethnomedicine
- 3.PMID: 39447789 (2024) — Endoperoxidases in biosynthesis of endoperoxide bonds. · International journal of biological macromolecules
- 4.PMID: 40364704 (2025) — Aromatherapy With Nardostachys Jatamansi DC. Essential Oil Targeting the MAOA Gene Regulates Cardiac Neural Remodeling and Amino Acid Metabolism to Alleviate Sleep Deprivation-Induced Myocardial Injury. · FASEB journal : official publication of the Federation of American Societies for Experimental Biology
- 5.PMID: 34265296