Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Methanol extract of leaves and its flavonoid-rich fraction ameliorated neurological deficits, cerebral oxidative stress, and neurochemical disturbances in AlCl3-induced rats [PMID:28697918]
Aqueous and ethyl acetate leaf extracts showed hypoglycemic effects in alloxan-induced diabetic mice [PMID:29651878]. Fruit fractions inhibited alpha-glucosidase activity in vitro [PMID:38867199].
Fruit extract inhibited proliferation and induced cell death in stage 4 Neuroblastoma cell lines [PMID:36029541] and showed synergistic cytotoxicity with cisplatin in HT-29 colorectal carcinoma cells [PMID:41515404]. Seed oils exhibited anti-proliferative effects on MCF-7 and MDA-MB-231 breast cancer cells [PMID:35129016].
Methanolic extract from leaves and fruit promoted wound healing in human normal epidermal keratinocyte (HaCaT) and foreskin fibroblast (BJ) cells [PMID:37300855]
Ethanolic fruit extract significantly anticipated puberty and increased body growth and sexual organ development in prepubertal male rats [PMID:30821486].
Synthèse des preuves
Sources PubMed
- 1.PMID: 37921076 (2024) — Therapeutic importance of Kigelia africana subsp. africana: an alternative medicine. · Natural product research
- 2.PMID: 27220655 (2016) — Kigelia africana (Lam.) Benth. (Sausage tree): Phytochemistry and pharmacological review of a quintessential African traditional medicinal plant. · Journal of ethnopharmacology
- 3.PMID: 28697918 (2017) — Sausage tree (Kigelia africana) flavonoid extract is neuroprotective in AlCl3-induced experimental Alzheimer's disease. · Pathophysiology : the official journal of the International Society for Pathophysiology
- 4.PMID: 32549404 (2020) — Ethnobotany, Phytochemistry and Pharmacological Activity of Kigelia africana (Lam.) Benth. (Bignoniaceae). · Plants (Basel, Switzerland)
- 5.PMID: 37300855