Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Banxia-Houpo-Tang (BHT) alone showed efficacy similar to antidepressants alone in improving Hamilton depression scale (HAMD) scores, while a combination of BHT and antidepressants led to more significant improvement [PMID:37224584].
A combination of honokiol, magnolol, and baicalin (HMB) significantly outperformed mono- or bi-agent treatments in reducing tumor growth and was comparable in efficacy to the FOLFIRI regimen [PMID:39950759].
Neolignans (honokiol, magnolol, 4-O-methylhonokiol, and obovatol) alleviated behavioral abnormalities, learning and cognitive impairments in animal models by inhibiting Aβ generation/aggregation and neuroinflammation [PMID:38955265].
Honokiol-rich standardized extract of M. officinalis bark produced an antiallodynic effect in SNI mice and reduced spinal neuroinflammation markers [PMID:37627513].
Honokiol administration significantly suppressed mast cell accumulation, inflammation, and serum immunoglobulin E levels in DNCB-induced mouse models [PMID:35074454].
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 39950759 (2025) — Honokiol-Magnolol-Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti-PD-1 Immunotherapy in Colorectal Cancer by Triggering GSDME-Dependent Pyroptosis. · Advanced science (Weinheim, Baden-Wurttemberg, Germany)
- 2.PMID: 36738944 (2023) — Huanglian-Houpo extract attenuates DSS-induced UC mice by protecting intestinal mucosal barrier and regulating macrophage polarization. · Journal of ethnopharmacology
- 3.PMID: 28271656 (2017) — Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents. · Journal of Zhejiang University. Science. B
- 4.PMID: 39372674 (2024) — A Comprehensive Review of Coptidis Rhizoma and Magnoliae Officinalis Cortex Drug Pair and Their Chemical Composition, Pharmacological Effects and Pharmacokinetics Analysis. · Drug design, development and therapy
- 5.PMID: 27721050