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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Pastinaca sativa (parsnip) is a biennial root vegetable with nutritional and medicinal properties [PMID: 33833896, PMID: 42110206], though it is known to cause phototoxic skin reactions upon UV exposure [PMID: 25317269, PMID: 29630166].
Contexte
Pastinaca sativa, commonly known as wild parsnip, is a biennial root vegetable of the Apiaceae family originating from Eurasia [PMID: 42110206]. It is used globally as a food source, animal feed, and in traditional medicine [PMID: 37457187, PMID: 42110206].
Usages traditionnels
In Iranian Traditional Medicine (ITM), parsnip (zardak) is used as a laxative, diuretic, kidney stone crusher, libido enhancer, and fertile agent [PMID: 33833896, PMID: 31429690]. It is also recognized in ITM as a stomach astringent, liver and uterine tonic, and a stimulant for ovulation [PMID: 31429690].
Composés actifs
The plant contains furanocoumarins (including xanthotoxin, bergapten, isopimpinellin, and imperatorin) [PMID: 31173794, PMID: 28309316], coumarins, polyacetylenes, essential oils (rich in octyl acetate and octyl butanoate), flavonoids, terpenoids, and polyphenols [PMID: 33833896, PMID: 40733297, PMID: 42110206].
Mécanisme d'action
Furanocoumarins in the plant act as photosensitizing compounds that, upon activation by UV light, interact with oxygen to produce reactive oxygen species, leading to tissue damage [PMID: 29630166, PMID: 39202761].
Preuves cliniques
Preuve DPhytophotodermatitis
Exposure to the plant followed by sunlight causes a non-immunologic skin reaction manifesting as erythema, blistering, edema, and hyperpigmentation [PMID: 25317269, PMID: 29630166, PMID: 39202761].
Preuve DPhotosensitization (Veterinary)
Ingestion or cutaneous application in horses and goats can lead to superficial necrotizing dermatitis, blepharitis, conjunctivitis, and corneal edema [PMID: 31173794, PMID: 35219345].
Sécurité et effets indésirables
The plant can cause phytophotodermatitis, a phototoxic reaction resulting in burning, painful rashes, and blisters upon UV exposure [PMID: 29630166, PMID: 39202761].
Synthèse des preuves
The available evidence consists primarily of case reports (D) regarding phototoxicity and review articles (C) regarding traditional uses and phytochemical composition; there are no high-level clinical trials or meta-analyses provided.
Sources PubMed
1.PMID: 31173794 (2019) — Wild parsnip (Pastinaca sativa)-induced photosensitization. · Toxicon : official journal of the International Society on Toxinology
2.PMID: 25317269 (2014) — Lime-induced phytophotodermatitis. · Journal of community hospital internal medicine perspectives
3.PMID: 26918393 (2016) — Molecular evolution of parsnip (Pastinaca sativa) membrane-bound prenyltransferases for linear and/or angular furanocoumarin biosynthesis. · The New phytologist
4.PMID: 37457187 (2023) — Morphological characterizations of parsnip (Pastinaca sativa L.) to select superior genotypes. · Food science & nutrition
5.PMID: 35219345 (2022) — Photodermatitis and ocular changes in nine horses after ingestion of wild parsnip (pastinaca sativa).
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 33833896 (2021) — Review of Pharmacological Properties and Chemical Constituents of Pastinaca sativa. · Journal of pharmacopuncture
7.PMID: 31429690 (2020) — The Parsnip (Pastinaca sativa L), A Proposed Remedy as to a Fertile Agent in the Viewpoint of Iranian Traditional Medicine. · Current drug discovery technologies
8.PMID: 30562630 (2019) — Evaluation of furanocoumarins from seeds of the wild parsnip (Pastinaca sativa L. s.l.). · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
10.PMID: 40733297 (2025) — South Tyrol (Italy) Pastinaca sativa L. subsp. sativa Essential Oil: GC-MS Composition, Antimicrobial, Anti-Biofilm, and Antioxidant Properties. · Molecules (Basel, Switzerland)
11.PMID: 41559852 (2026) — Chromosomal-scale genome assembly of parsnip (Pastinaca sativa) reveals genome evolution and carotenoid regulation. · Plant physiology
12.PMID: 28309316 (1981) — Patterns of furanocoumarin production and insect herbivory in a population of wild parsnip (Pastinaca sativa L.). · Oecologia
13.PMID: 39202761 (2024) — New Insights Concerning Phytophotodermatitis Induced by Phototoxic Plants. · Life (Basel, Switzerland)
14.PMID: 42110206 (2026) — Pastinaca sativa L.: Nutritional Composition, Phytochemistry, and Pharmacological Properties Supporting Its Potential as a Functional Food and Therapeutic Agent. · Food science & nutrition
15.PMID: 32079080 (2020) — Antioxidant Activity of Pastinaca sativa L. ssp. sylvestris [Mill.] Rouy and Camus Essential Oil. · Molecules (Basel, Switzerland)