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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Pausinystalia macroceras
Central African tree related to yohimbe with milder action.
Pausinystalia macroceras, a Central African tree related to yohimbe, is used as a mild stimulant and aphrodisiac, with traditional applications for fatigue and low libido. Its bark contains lower levels of yohimbine along with corynanthine and pseudoyohimbine, which contribute to its milder pharmacological profile compared to yohimbe. Evidence is limited (Level C), with some pilot studies suggesting antimalarial potential.
The primary active compound yohimbine acts as a selective alpha-2 adrenergic receptor antagonist, increasing norepinephrine release and sympathetic outflow, which can enhance arousal and libido. Corynanthine, a stereoisomer, exhibits alpha-1 adrenergic antagonism, potentially contributing to vasodilation and reduced hypertensive effects. Pseudoyohimbine may have additional dopaminergic activity, though its clinical significance is unclear. The antimalarial effect is thought to involve inhibition of heme polymerization in Plasmodium parasites.
Central African tree related to yohimbe with milder action.
Pausinystalia macroceras, a Central African tree related to yohimbe, is used as a mild stimulant and aphrodisiac, with traditional applications for fatigue and low libido. Its bark contains lower levels of yohimbine along with corynanthine and pseudoyohimbine, which contribute to its milder pharmacological profile compared to yohimbe. Evidence is limited (Level C), with some pilot studies suggesting antimalarial potential.
The primary active compound yohimbine acts as a selective alpha-2 adrenergic receptor antagonist, increasing norepinephrine release and sympathetic outflow, which can enhance arousal and libido. Corynanthine, a stereoisomer, exhibits alpha-1 adrenergic antagonism, potentially contributing to vasodilation and reduced hypertensive effects. Pseudoyohimbine may have additional dopaminergic activity, though its clinical significance is unclear. The antimalarial effect is thought to involve inhibition of heme polymerization in Plasmodium parasites.