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Not CommonRésumée par IA
Pelargonium Graveolens
Pelargonium graveolens
Aromatherapy and skin care in European herbal tradition
How does Pelargonium graveolens essential oil work for anxiety?
Pelargonium graveolens essential oil contains geraniol and citronellol, which have demonstrated anxiolytic properties through interaction with GABAergic and serotonergic systems. These compounds modulate neurotransmitter activity in the brain, producing calming effects. The aromatic compounds are absorbed through the olfactory system, triggering limbic system responses that influence mood and emotional regulation. Evidence Level: C (preclinical studies support these mechanisms, though human clinical trials are limited).
Does Pelargonium graveolens essential oil interact with medications?
There are no well-documented drug interactions for topical or aromatherapy use of Pelargonium graveolens essential oil. However, geraniol and citronellol may theoretically affect liver enzyme pathways (CYP450) that metabolize certain medications. Internal use of the essential oil should be avoided due to potential toxicity. Patients taking sedatives, antidepressants, or medications metabolized by the liver should consult a healthcare provider before use. Evidence Level: C (based on constituent analysis and theoretical interactions).
What is the recommended dosage for Pelargonium graveolens essential oil?
For aromatherapy, use 2-3 drops of Pelargonium graveolens essential oil in a diffuser or diluted in a carrier oil for topical application. For skin applications, dilute to 1-3% concentration (approximately 1-3 drops per teaspoon of carrier oil) to minimize skin sensitization risk. Internal use of the essential oil is not recommended due to safety concerns. Evidence Level: Traditional use guidelines.
Is Pelargonium graveolens essential oil safe during pregnancy?
Pelargonium graveolens essential oil is considered unsafe during pregnancy and should be avoided. The essential oil contains compounds that may stimulate uterine contractions or affect hormonal balance. Pregnant women, those trying to conceive, and breastfeeding mothers should not use this essential oil without explicit guidance from a qualified healthcare provider. Evidence Level: C (based on constituent properties and traditional contraindications).
Can Pelargonium graveolens help with skin infections and wound healing?
Pelargonium graveolens essential oil has demonstrated antimicrobial activity against various bacteria and fungi in laboratory studies, attributed to compounds like geraniol and citronellol. Traditionally, it has been used topically as an antiseptic for minor wounds and skin infections. However, the essential oil must be properly diluted (1-3% in carrier oil) to prevent contact dermatitis and skin sensitization. Evidence Level: C (preclinical evidence supports antimicrobial properties).
Does Pelargonium graveolens help with menopausal symptoms?
Pelargonium graveolens essential oil is traditionally used in aromatherapy to support menopausal symptom management, particularly for mood fluctuations and anxiety. Some practitioners suggest it may help balance hormones, though clinical evidence is limited. The calming properties attributed to geraniol and citronellol may provide relief from stress and emotional symptoms associated with menopause. Evidence Level: C (traditional use with limited clinical validation).
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 29 articles PubMed · modèle : gemma4:31b
Résumé
Pelargonium graveolens, also known as rose-scented geranium, is an aromatic medicinal plant valued for its essential oil used in fragrance, cosmetics, and traditional medicine [PMID:38574692, 35170422].
Contexte
Pelargonium graveolens is an economically important aromatic plant from the Geraniaceae family [PMID:31679416, 38574692]. It is characterized by the production of essential oils primarily in its glandular trichomes [PMID:38574692, 33949016].
Usages traditionnels
In Palestine, leaves are used in traditional medicine to relieve respiratory, gastrointestinal, dental, and cardiovascular disorders, and are used as tea or food additives [PMID:36080486]. In Morocco and Algeria, it is used as a remedy for various illnesses, including the management of diabetes [PMID:35170422].
Composés actifs
The essential oil primarily contains mono- and sesquiterpenes [PMID:38574692]. Major constituents identified across studies include citronellol, geraniol, citronellyl formate, geranyl formate, iso-menthone, and linalool [PMID:30000892, 31679416, 34310905, 36080486]. Leaf and flower extracts also contain flavonoids such as kaempferol and quercetin derivatives [PMID:23027699].
Mécanisme d'action
The oil exhibits antioxidant and anti-inflammatory properties [PMID:34310905, 37819493]. It has demonstrated the ability to inhibit $\alpha$-glucosidase [PMID:36080486] and protect against hepato-renal toxicity by reducing serum levels of liver enzymes (AST, ALT) and renal markers (urea, creatinine) [PMID:39698236].
Preuves cliniques
Preuve CStress and Anxiety
The natural scent of P. graveolens 'Dr. Westerlund' had positive effects on stress reduction [PMID:37298987]; the oil is used as an anxiolytic aromatherapy agent to relieve anxiety, stress, and depression [PMID:19831048].
Preuve DCefotaxime-induced hepato-renal toxicity
Oral administration of geranium oil (67 mg/kg b.w./day) significantly reduced liver and kidney damage in rats [PMID:39698236].
Preuve DParkinsonian model (MPTP-induced)
Oral treatment improved motor performance (rotarod latency and distance) and prevented dopaminergic neuron death in mice [PMID:37819493].
Preuve DDiabetes (STZ-induced rats)
Aqueous leaf extract (40 mg/kg) was investigated for antihyperglycemic activity [PMID:35170422].
Preuve CNeuropathic pain and skin issues
Topical application has been used for neuropathic pain and cracked nipples during breastfeeding, though these claims have not been scientifically validated [PMID:30000892].
Sécurité et effets indésirables
The essential oil is considered an irritant to the skin and eyes, and a skin and respiratory sensitizer [PMID:37522103].
Grossesse et allaitement
Topical application of fresh leaves or oil in calendula cream has been used for cracked nipples during breastfeeding, though not scientifically validated [PMID:30000892].
Synthèse des preuves
Evidence is primarily based on in vitro studies and animal models (rats/mice), with limited systematic reviews on chemical composition. Human clinical data is lacking, and many traditional uses remain scientifically unvalidated.
Sources PubMed
1.PMID: 37895122 (2023) — Plant Extracts as Skin Care and Therapeutic Agents. · International journal of molecular sciences
2.PMID: 30000892 (2006) — Herbal Extracts with Antifungal Activity against Candida albicans: A Systematic Review. · Mini reviews in medicinal chemistry
3.PMID: 37298987 (2023) — Odor Perception and Descriptions of Rose-Scented Geranium Pelargonium graveolens 'Dr. Westerlund'-Sensory and Chemical Analyses. · Molecules (Basel, Switzerland)
4.PMID: 38574692 (2024) — Isoprenyl diphosphate synthases of terpenoid biosynthesis in rose-scented geranium (Pelargonium graveolens). · Plant physiology and biochemistry : PPB
5.PMID: 31679416 (2021) — Studies on essential oil from rose-scented geranium, Pelargonium graveolens L'Hérit. (Geraniaceae).
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 34310905 (2022) — [Rose-scented geranium essential oil from Algeria (Pelargonium graveolens L'Hérit.): Assessment of antioxidant, anti-inflammatory and anticancer properties against different metastatic cancer cell lines]. · Annales pharmaceutiques francaises
7.PMID: 33949016 (2021) — Cytosolic geraniol and citronellol biosynthesis require a Nudix hydrolase in rose-scented geranium (Pelargonium graveolens). · The Plant journal : for cell and molecular biology
8.PMID: 26696243 (2016) — Performance of rose scented geranium (Pelargonium graveolens) in heavy metal polluted soil vis-à-vis phytoaccumulation of metals. · International journal of phytoremediation
9.PMID: 37522103 (2023) — Safety and efficacy of a feed additive consisting of an essential oil from the herbaceous parts of Pelargonium graveolens L'Hér. (geranium rose oil) for all animal species (FEFANA asbl). · EFSA journal. European Food Safety Authority
10.PMID: 12118700 (2002) — Water soluble fractions of rose-scented geranium (Pelargonium species) essential oil. · Bioresource technology
11.PMID: 39698236 (2024) — Protective effects of Pelargonium graveolens (geranium) oil against cefotaxime-induced hepato-renal toxicity in rats. · Frontiers in toxicology
12.PMID: 34947021 (2021) — Harnessing Endophytic Fungi for Enhancing Growth, Tolerance and Quality of Rose-Scented Geranium (Pelargonium graveolens (L'Hér) Thunb.) Plants under Cadmium Stress: A Biochemical Study. · Journal of fungi (Basel, Switzerland)
14.PMID: 33556110 (2021) — Bioactivities of rose-scented geranium nanoemulsions against the larvae of Anopheles stephensi and their gut bacteria. · PloS one
15.PMID: 35170422 (2022) — Effect of Pelargonium graveolens on Glucose Metabolism in Streptozotocin- Induced Diabetic Rats. · Cardiovascular & hematological disorders drug targets
16.PMID: 25194330 (2014) — Impact of plant growth promoting Pseudomonas monteilii PsF84 and Pseudomonas plecoglossicida PsF610 on metal uptake and production of secondary metabolite (monoterpenes) by rose-scented geranium (Pelargonium graveolens cv. bourbon) grown on tannery sludge amended soil. · Chemosphere
17.PMID: 23027699 (2013) — Chemical composition and biological activities of polar extracts and essential oil of rose-scented geranium, Pelargonium graveolens. · Phytotherapy research : PTR
18.PMID: 12477000 (2002) — Weed control in rose-scented geranium (Pelargonium spp). · Pest management science
19.PMID: 35803943 (2022) — Preparation of geranium oil formulations effective for control of phenotypic resistant cattle tick Rhipicephalus annulatus. · Scientific reports
20.PMID: 39280190 (2024) — Cytotoxic properties of Pelargonium graveolens leaf extract and its green-synthesized gold nanoparticles (in vitro study). · Journal of Taibah University Medical Sciences
21.PMID: 41126041 (2025) — Evaluation of in vitro-geranium (Pelargonium graveolens) plants affected by irradiation and chemical mutagens. · BMC plant biology
22.PMID: 36080486 (2022) — Chemical Markers and Pharmacological Characters of Pelargonium graveolens Essential Oil from Palestine. · Molecules (Basel, Switzerland)
23.PMID: 39044015 (2024) — Heterologous expression of ACC deaminase gene in Pelargonium graveolens showed elevated tolerance to chromium stress. · Transgenic research
24.PMID: 23074914 (2012) — A somaclonal variant of rose-scented geranium (Pelargonium spp.) with moderately high content of isomenthone in its essential oil. · Natural product communications
25.PMID: 37819493 (2023) — Therapeutic Effects of Geranium Oil in MPTP-Induced Parkinsonian Mouse Model. · Plant foods for human nutrition (Dordrecht, Netherlands)
26.PMID: 36079608 (2022) — Chemical Profiling and Biological Activities of Pelargonium graveolens Essential Oils at Three Different Phenological Stages. · Plants (Basel, Switzerland)
27.PMID: 11101151 (2000) — Characterization of geranium (Pelargonium graveolens) chloroplast EF-Tu cDNA. · Molecules and cells
28.PMID: 17721867 (2008) — Carbonate extraction process for the metabolic, isozymic and proteomic profiling of rose-scented geranium (Pelargonium sp.), a hyper-acidic plant. · Phytochemical analysis : PCA
29.PMID: 30508331 (2016) — Characterization of 12-Oxophytodienoic Acid Reductases from Rose-scented Geranium (Pelargonium graveolens). · Natural product communications