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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Paeonia lactiflora + Glycyrrhiza
Classical TCM formula for PCOS, high androgens, and muscle cramping.
The Peony and Licorice Combo (Paeonia lactiflora + Glycyrrhiza) is a classical Traditional Chinese Medicine formula used for polycystic ovary syndrome (PCOS), hyperandrogenism, and muscle cramping. Its primary active compounds include paeoniflorin, glycyrrhizin, albiflorin, and liquiritigenin, which collectively modulate androgen levels, aromatase activity, and smooth muscle tone. Clinical evidence (Grade B) supports its use in reducing serum testosterone and improving menstrual regularity in PCOS patients.
Paeoniflorin exerts anti-inflammatory and antispasmodic effects via modulation of the HPA axis and inhibition of NF-κB signaling, while glycyrrhizin inhibits 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2), leading to increased cortisol availability and subsequent suppression of adrenal androgen production. Liquiritigenin acts as a selective aromatase modulator, reducing peripheral conversion of androgens to estrogens, and may also bind to estrogen receptors. Additionally, the combination enhances GABAergic activity, contributing to muscle relaxation and relief from cramping.
Classical TCM formula for PCOS, high androgens, and muscle cramping.
The Peony and Licorice Combo (Paeonia lactiflora + Glycyrrhiza) is a classical Traditional Chinese Medicine formula used for polycystic ovary syndrome (PCOS), hyperandrogenism, and muscle cramping. Its primary active compounds include paeoniflorin, glycyrrhizin, albiflorin, and liquiritigenin, which collectively modulate androgen levels, aromatase activity, and smooth muscle tone. Clinical evidence (Grade B) supports its use in reducing serum testosterone and improving menstrual regularity in PCOS patients.
Paeoniflorin exerts anti-inflammatory and antispasmodic effects via modulation of the HPA axis and inhibition of NF-κB signaling, while glycyrrhizin inhibits 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2), leading to increased cortisol availability and subsequent suppression of adrenal androgen production. Liquiritigenin acts as a selective aromatase modulator, reducing peripheral conversion of androgens to estrogens, and may also bind to estrogen receptors. Additionally, the combination enhances GABAergic activity, contributing to muscle relaxation and relief from cramping.