Fiche d'information compilée à partir de PubMed
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Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Pheasant's Eye (Adonis vernalis) is a member of the Ranunculaceae family native to Europe and Asia, recognized for its cardiac-enhancing effects [PMID:30778296].
Contexte
Adonis vernalis L. is a herbaceous species that evolved in the southern part of Europe during the Pleistocene and migrated eastwards into the continental forest-steppe zone [PMID:30778296, PMID:36352030].
Usages traditionnels
Species of the genus Adonis have long been used in European and Chinese folk medicine due to their cardiac-enhancing effects [PMID:30778296].
Composés actifs
The most important components are cardiac glycosides, along with flavones, carotenoids, coumarins, and other structural types; more than 120 chemical compounds have been isolated [PMID:30778296].
Mécanisme d'action
The plants possess cardiovascular activity and are noted for their cardiotonic effects [PMID:30778296, PMID:27748195].
Preuves cliniques
Preuve CCardiovascular disorders
Adonis vernalis is recognized as a cardiotonic plant, although there are very few clinical studies available on the source plant [PMID:27748195]
Sécurité et effets indésirables
The genus Adonis contains toxic components; for example, A. microcarpa caused vomiting, rapid and shallow breathing, and death in pigs [PMID:2735892]. A related species, A. aestivalis, caused gastrointestinal gaseous distension, myocardial necrosis, and death in horses [PMID:15133169]. Safety assessments of homeopathic preparations of A. vernalis highlight the need for caution due to the plant's inherent toxicity [PMID:32618363].
Synthèse des preuves
The evidence consists primarily of reviews and veterinary case reports; there is a lack of high-level human clinical trial data.
Sources PubMed
- 1.PMID: 30778296 (2019) — The Genus Adonis as an Important Cardiac Folk Medicine: A Review of the Ethnobotany, Phytochemistry and Pharmacology. · Frontiers in pharmacology
- 2.PMID: 32618363 (2020) — Safety assessment of homeopathic medicines: The Adonis vernalis paradox and the 'analysis trap' of using different pharmacopeias. · Journal of applied toxicology : JAT
- 3.PMID: 15133169 (2004) — Summer pheasant's eye (Adonis aestivalis) poisoning in three horses. · Veterinary pathology
- 4.PMID: 36352030 (2022) — Genotyping-by-sequencing reveals range expansion of Adonis vernalis (Ranunculaceae) from Southeastern Europe into the zonal Euro-Siberian steppe. · Scientific reports
- 5.PMID: 27748195 (2017) — Adonis sp., Convallaria sp., Strophanthus sp., Thevetia sp., and Leonurus sp. - Cardiotonic Plants with Known Traditional Use and a Few Preclinical and Clinical Studies.