Pineapple Sage (Salvia elegans): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Pineapple Sage work to reduce anxiety?

Pineapple Sage exerts its calming effects primarily through volatile oils like linalool and linalyl acetate. These compounds are believed to modulate GABA receptors in the central nervous system, which helps slow down nerve activity and promote relaxation. Rosmarinic acid contributes additional antioxidant and neuroprotective benefits. While specific clinical trials are limited, the mechanism is consistent with other anxiolytic herbs in the Salvia genus (Evidence Level B).

Can I take Pineapple Sage if I am on blood thinners?

You should exercise caution and consult a physician before taking Pineapple Sage if you are on blood thinners. Salvia species may contain compounds that affect platelet aggregation or interact with anticoagulant medications, potentially increasing the risk of bleeding. Because Pineapple Sage can also cause mild sedation, it may compound the effects of other medications. Professional guidance is essential to avoid adverse interactions (Evidence Level C).

What is the recommended dosage for Pineapple Sage tea?

The standard adult dosage for Pineapple Sage is 2 to 4 grams of fresh or dried leaf prepared as a tea, taken once daily. To prepare, steep the leaves in boiling water for 5 to 10 minutes to extract the volatile oils. This dosage is based on traditional usage guidelines for managing mild anxiety and digestive discomfort. Users should start with a lower amount to assess individual tolerance (Evidence Level Traditional).

Is Pineapple Sage safe to use during pregnancy?

Pineapple Sage is considered unsafe during pregnancy and should be avoided. Many Salvia species can stimulate uterine contractions, which poses a risk of miscarriage or premature labor, particularly at therapeutic doses. While culinary amounts may be less risky, medicinal use is explicitly contraindicated. Women who are pregnant or breastfeeding should consult a qualified healthcare provider before using this herb (Evidence Level D).

What are the main benefits of Pineapple Sage?

Pineapple Sage is traditionally used for its mild anxiolytic and digestive properties. In Mexican folk medicine, it is valued for calming the nervous system, relieving stress, and soothing gastrointestinal upset. The herb contains flavonoids and rosmarinic acid, which provide antioxidant support. Current evidence supports its use as a gentle relaxant and digestive aid, though robust clinical data is still emerging (Evidence Level B).

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Salvia elegans is a medicinal herb used traditionally in Mexico for nervous disorders and hypertension, demonstrating anxiolytic, antidepressant, and antihypertensive activities in animal models [PMID:39274918, PMID:20488233, PMID:16530995].

Contexte

Salvia elegans Vahl, also known as 'mirto', is a shrub belonging to the Lamiaceae family [PMID:16530995, PMID:20488233].

Usages traditionnels

In Mexico, it is commonly used as a remedy for nervous disorders, inflammatory diseases, and 'ringing in the ears', the latter of which may be associated with arterial hypertension and arteriosclerotic conditions [PMID:39274918, PMID:16530995].

Composés actifs

Identified compounds include phenolic compounds, terpenes, oleanolic acid [PMID:32347111, PMID:34568977], and the flavanone isosakuranetin-5-O-rutinoside [PMID:24165584]. Essential oils contain borneol (17.4%), β-eudesmol (10.4%), bornyl acetate (5%), and guaiol (4.8%) [PMID:25531412]. Leaves also contain secoisopimaranes, specifically 3,4-secoisopimara-7,15-dien-3-oic acid [PMID:41062670].

Mécanisme d'action

Phenolic compounds from S. elegans exhibit inhibitory effects on the Angiotensin I-converting enzyme (ACE) [PMID:32347111]. The plant also shows inhibitory activity against α-glucosidase [PMID:30513773] and interacts with serotonergic drugs (5-HT1A and 5-HT2) to produce anxiolytic and antidepressant effects [PMID:34568977].

Preuves cliniques

Preuve DHypertension

Hydroalcoholic extract (SeHA) significantly decreased systolic blood pressure in mice and showed an antihypertensive effect greater than losartan [PMID:20488233]

Preuve DAnxiety and Depression

Hydroalcoholic extracts and isolated compounds (such as isosakuranetin-5-O-rutinoside) induced anxiolytic and antidepressant-like effects in mice and rats, as evidenced by the forced swimming test and elevated plus-maze [PMID:16413718, PMID:16530995, PMID:24165584, PMID:34568977]

Preuve DBacterial Infection (S. aureus)

Secoisopimaranes from leaves showed potent antimicrobial activity against Staphylococcus aureus (MIC = 15.6 µg/mL) [PMID:41062670]

Preuve DMetabolic Syndrome

S. elegans decoction was found to be an effective inhibitor of α-glucosidase [PMID:30513773]

Interactions médicamenteuses

Compounds isolated from S. elegans interact with serotoninergic drugs (5-HT1A and 5-HT2) [PMID:34568977].

Synthèse des preuves

The current evidence is based exclusively on in vitro studies and animal models (mice and rats); there are no human clinical trials provided.

Sources PubMed

1.PMID: 32347111 (2021) — Angiotensin-converting enzyme inhibitors from Salvia elegans Vahl. · Natural product research
2.PMID: 34568977 (2021) — Antidepressant and anxiolytic compounds isolated from Salvia elegans interact with serotonergic drugs. · Naunyn-Schmiedeberg's archives of pharmacology
3.PMID: 41062670 (2025) — Secoisopimaranes from Salvia elegans Vahl leaves as antibacterial agents against Staphylococcus aureus. · Scientific reports
4.PMID: 30513773 (2018) — Salvia elegans, Salvia greggii and Salvia officinalis Decoctions: Antioxidant Activities and Inhibition of Carbohydrate and Lipid Metabolic Enzymes. · Molecules (Basel, Switzerland)
5.PMID: 39274918 (2024) — Salvia elegans Vahl Counteracting Metabolic Syndrome and Depression in Mice on a High-Fat Diet.

Pineapple Sage

Sources et citations

Calculer une dose sûre de Pineapple Sage

Jordan Sage

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Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Interactions médicamenteuses

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Pineapple Sage

Sources et citations

Calculer une dose sûre de Pineapple Sage

Plantes associées

Jordan Sage

Mexican Sage

Rosemary

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Interactions médicamenteuses

Synthèse des preuves

Sources PubMed

Sources gouvernementales