Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Composés actifs
Mécanisme d'action
Preuves cliniques
Long-term treatment (12+ weeks) showed significant decreases in symptom scores and increases in maximum and average urine flow rates, though prostatic volume remained unchanged in the short term [PMID:7538904]. Other reviews note mixed efficacy results with significant confounders like poor product standardization [PMID:27180172]. In a comparative trial, tamsulosin and a combination of tamsulosin and cernitin were more effective than cernitin alone for urinary disturbance [PMID:12094707].
Cernitin pollen extract was used as add-on therapy to alpha-blockers, showing significant improvement in NIH-CPSI total, pain, and quality of life sub-scores at 12 weeks [PMID:32648985].
Administration of cernitin pollen extract for 30 days resulted in a significant mean decrease in serum PSA levels (-0.6 ± 1.4 ng/mL) [PMID:29577437]. However, a review of RCTs concluded that evidence for most dietary factors, including cernitin, is inadequate to recommend their use for down-regulating PSA in men with prostate cancer or increased risk [PMID:33003518].
A randomized, double-blind, placebo-controlled study investigated the efficacy of nonsolvent flower pollen extracts (Graminex RCT Fem UI and Graminex PollenBerry) on UI in healthy women over 24 weeks [PMID:39219633].
Posologie et administration
Synthèse des preuves
Sources PubMed
- 1.PMID: 35692639 (2022) — The complete chloroplast genome of weedy rye Secale cereale subsp. segetale. · Mitochondrial DNA. Part B, Resources
- 2.PMID: 16988347 (2006) — Rye (Secale cereale L.). · Methods in molecular biology (Clifton, N.J.)
- 3.PMID: 33003518 (2020) — Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials. · Nutrients
- 4.PMID: 27180172 (2016) — Phytotherapy for Benign Prostatic Hyperplasia. · Current urology reports
- 5.PMID: 32648985 (2020) — Comparison of cernitin pollen extract vs tadalafil therapy for refractory chronic prostatitis/chronic pelvic pain syndrome: A randomized, prospective study.