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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Wolfiporia extensa
Outer brown skin of the poria mushroom used in TCM specifically for its stronger diuretic and edema-resolving properties compared to the white inner flesh.
Poria Cocos Skin, the outer brown layer of the fungus Wolfiporia extensa, is a traditional Chinese medicine renowned for its potent diuretic and anti-edematous properties, surpassing the inner flesh in these actions. It is primarily used to treat edema, urinary blockage, and dampness-related skin conditions, with key active compounds including pachymic acid, polyporenic acid C, tumulosic acid, and beta-glucans. Despite limited modern clinical evidence, its pharmacological profile supports applications in fluid retention and inflammatory skin disorders.
Poria Cocos Skin exerts its diuretic effect primarily through inhibition of renal Na+/K+-ATPase and modulation of aquaporin channels, particularly AQP2, reducing water reabsorption. Its anti-inflammatory actions are mediated by suppression of COX-2 and LOX pathways, decreasing prostaglandin and leukotriene synthesis. Additionally, pachymic acid and beta-glucans activate macrophages via dectin-1 receptors, enhancing immune modulation while triterpene acids inhibit NF-κB signaling, reducing cytokine production.
Outer brown skin of the poria mushroom used in TCM specifically for its stronger diuretic and edema-resolving properties compared to the white inner flesh.
Poria Cocos Skin, the outer brown layer of the fungus Wolfiporia extensa, is a traditional Chinese medicine renowned for its potent diuretic and anti-edematous properties, surpassing the inner flesh in these actions. It is primarily used to treat edema, urinary blockage, and dampness-related skin conditions, with key active compounds including pachymic acid, polyporenic acid C, tumulosic acid, and beta-glucans. Despite limited modern clinical evidence, its pharmacological profile supports applications in fluid retention and inflammatory skin disorders.
Poria Cocos Skin exerts its diuretic effect primarily through inhibition of renal Na+/K+-ATPase and modulation of aquaporin channels, particularly AQP2, reducing water reabsorption. Its anti-inflammatory actions are mediated by suppression of COX-2 and LOX pathways, decreasing prostaglandin and leukotriene synthesis. Additionally, pachymic acid and beta-glucans activate macrophages via dectin-1 receptors, enhancing immune modulation while triterpene acids inhibit NF-κB signaling, reducing cytokine production.