Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Qu Mai acts as a natural diuretic by increasing the excretion of water and sodium from the body. Its active compounds, specifically saponins and flavonoids, are thought to inhibit renal tubular reabsorption, which helps clear heat and dampness from the bladder. This mechanism explains its traditional use in treating urinary tract infections and edema. Evidence level: C/Traditional.
Does Qu Mai interact with prescription medications?
Qu Mai has the potential to interact with diuretic medications, such as furosemide or hydrochlorothiazide. Because Dianthus superbus increases urine output, combining it with pharmaceutical diuretics may lead to dehydration or electrolyte imbalances. It may also potentiate the effects of antihypertensive drugs. Patients taking prescription medications should consult a healthcare provider before use. Evidence level: C (theoretical).
What is the standard dosage for Qu Mai (Dianthus superbus)?
The standard adult dosage for Qu Mai is generally 6 to 10 grams daily when prepared as a water decoction. The herb is typically boiled in water to create a tea intended for immediate consumption. Dosage may vary depending on whether it is used alone or in combination with other herbs in a formula. Evidence level: Traditional.
Is Qu Mai safe to take during pregnancy?
No, Qu Mai is considered unsafe during pregnancy and is contraindicated for pregnant women. Dianthus superbus promotes blood circulation and stimulates the uterus, which poses a risk of miscarriage or premature labor. Due to these strong emmenagogue properties, it should be strictly avoided by anyone who is pregnant or trying to conceive. Evidence level: Traditional.
What is Qu Mai used for in Traditional Chinese Medicine?
Qu Mai is primarily used to clear heat, promote urination, and break up blood stasis. It is commonly prescribed for urinary tract infections (UTIs), hematuria (blood in urine), and urinary stones due to its antiseptic and diuretic properties. Additionally, it is used to treat amenorrhea (absence of menstruation) by promoting blood flow. Evidence level: C.
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Qu Mai (Dianthus superbus) is a traditional medicinal herb used in Chinese and Mongolian medicine for its anti-inflammatory, diuretic, and immunomodulatory properties [PMID:35062995, 30841605, 27133261].
Contexte
Dianthus superbus L. (also known as Qu Mai or Dianthi herba) is a plant distributed across the northern hemisphere, including Asia, Africa, Oceania, and South America [PMID:35062995]. It is the dried aerial part of the plant [PMID:35062995].
Usages traditionnels
Traditionally used as a treatment for urethritis, carbuncles, carcinomas [PMID:27133261, 27279718], inflammation, pain, and immunological conditions [PMID:35425507], as well as a diuretic and anti-inflammatory agent [PMID:30841605, 27076746].
Composés actifs
Identified compounds include triterpenoid saponins (e.g., dianosides, DS-1) [PMID:35062995, 21467688, 25542429], flavonoids and flavone C-glycosides (e.g., 2''-O-rhamnosyllutonarin, quercetin 3-glucoside) [PMID:35062995, 40806041, 31765700], phytoecdysteroids (superecdysones A-F) [PMID:37178942], cyclic peptides (dianthins C-F) [PMID:15387653, 28920330], and phenolic acids such as vanillic acid and hydroferulic acid [PMID:27076746].
Mécanisme d'action
Mechanisms include the inhibition of acetylcholinesterase (AChE) and increase of brain-derived neurotropic factor (BDNF) expression in the hippocampus [PMID:27133261], modulation of lipid metabolism, insulin signaling, inflammation, and apoptosis pathways [PMID:40806041], and the upregulation of Foxp3 in CD4(+) T cells to induce regulatory T cells [PMID:23433080].
Preuves cliniques
Preuve DMemory Impairment
Attenuated learning and memory impairment induced by scopolamine in mice [PMID:27133261]
Preuve DDiabetic Nephropathy
Ameliorated blood glucose, insulin, HOMA-IR, HbA1c, and reduced glomerular fibrosis and renal dysfunction in db/db mice [PMID:30841605]
The current evidence is primarily based on in vitro studies and animal models (mice, zebrafish), indicating potential for neuroprotective, anti-inflammatory, and metabolic benefits, but lacks human clinical trial data. Genotoxicity was observed in cell cultures at high concentrations.
Sources PubMed
1.PMID: 37178942 (2023) — Phytoecdysteroids from Dianthus superbus L.: Structures and anti-neuroinflammatory evaluation. · Phytochemistry
2.PMID: 42031993 (2026) — Genotoxic potential of Dianthus superbus var. superbus and Petasites paradoxus (Retz.) Baumg. methanolic extracts in Chinese hamster ovary cells. · Scientific reports
3.PMID: 40806041 (2025) — Flavone C-Glycosides from Dianthus superbus L. Attenuate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) via Multi-Pathway Regulations. · Nutrients
4.PMID: 27133261 (2016) — Cognitive-Enhancing Effect of Dianthus superbus var. Longicalycinus on Scopolamine-Induced Memory Impairment in Mice. · Biomolecules & therapeutics
5.PMID: 30841605 (2019) — Dianthus superbus Improves Glomerular Fibrosis and Renal Dysfunction in Diabetic Nephropathy Model.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 28920330 (2016) — [Oligopeptides in plant medicines cited in Chinese Pharmacopoeia]. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
7.PMID: 35425507 (2022) — Preparative isolation of maltol glycoside from Dianthus superbus and its anti-inflammatory activity in vitro. · RSC advances
8.PMID: 29515317 (2018) — Salicylic acid promotes plant growth and salt-related gene expression in Dianthus superbus L. (Caryophyllaceae) grown under different salt stress conditions. · Physiology and molecular biology of plants : an international journal of functional plant biology
9.PMID: 38257252 (2024) — Impact of Preparative Isolation of C-Glycosylflavones Derived from Dianthus superbus on In Vitro Glucose Metabolism. · Molecules (Basel, Switzerland)
10.PMID: 27076746 (2016) — Neuroprotective Properties of Compounds Extracted from Dianthus superbus L. against Glutamate-induced Cell Death in HT22 Cells. · Pharmacognosy magazine
11.PMID: 27279718 (2016) — Simultaneous Determination of Eight Bioactive Compounds in Dianthus superbus by High-performance Liquid Chromatography. · Pharmacognosy magazine
12.PMID: 29019031 (2017) — Effects of different soil remediation methods on inhibition of lead absorption and growth and quality of Dianthus superbus L. · Environmental science and pollution research international
13.PMID: 31765700 (2020) — Probing the effect of quercetin 3-glucoside from Dianthus superbus L against influenza virus infection- In vitro and in silico biochemical and toxicological screening. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
14.PMID: 15387653 (2004) — New cytotoxic cyclic peptides and dianthramide from Dianthus superbus. · Journal of natural products
15.PMID: 23433080 (2013) — Immunosuppressive effects of the traditional Chinese herb Qu Mai on human alloreactive T cells. · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
16.PMID: 35062995 (2022) — Dianthi herba: a comprehensive review of its botany, traditional use, phytochemistry, and pharmacology. · Chinese medicine
17.PMID: 25354144 (2016) — The complete chloroplast genome sequence of Dianthus superbus var. longicalycinus. · Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis
18.PMID: 34512941 (2021) — Dianthus superbus as a critically endangered species in Latvia: evaluation of its growth conditions and conservation possibilities. · AoB PLANTS
19.PMID: 40647080 (2025) — Dianthus superbus L. (QM) Extract-Assisted Silver Nanoparticle Gelatin Films with Antioxidant and Antimicrobial Properties for Fresh Fruit Preservation. · Foods (Basel, Switzerland)
20.PMID: 21467688 (2011) — Three new triterpenoid saponins from Dianthus superbus. · Chemical & pharmaceutical bulletin
21.PMID: 28484476 (2017) — Salicylic Acid Alleviates the Adverse Effects of Salt Stress on Dianthus superbus (Caryophyllaceae) by Activating Photosynthesis, Protecting Morphological Structure, and Enhancing the Antioxidant System. · Frontiers in plant science
22.PMID: 26513163 (2015) — Analysis of the Complete Chloroplast Genome of a Medicinal Plant, Dianthus superbus var. longicalyncinus, from a Comparative Genomics Perspective. · PloS one
23.PMID: 29741311 (2017) — [Effects of the additives and the combination of plants on Pb absorption, growth and quality of Dianthus superbus]. · Ying yong sheng tai xue bao = The journal of applied ecology
24.PMID: 30654095 (2019) — Utilization of Dianthus superbus L and its bioactive compounds for antioxidant, anti-influenza and toxicological effects. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
25.PMID: 21961957 (2011) — Chinese herbal extracts of Rubia cordifolia and Dianthus superbus suppress IgE production and prevent peanut-induced anaphylaxis. · Chinese medicine
26.PMID: 36118003 (2022) — Mongolian medicine in treating type 2 diabetes mellitus combined with nonalcoholic fatty liver disease via FXR/LXR-mediated P2X7R/NLRP3/NF-κB pathway activation. · Chinese herbal medicines
27.PMID: 17340306 (1984) — Structures of Dianosides G, H and I, Triterpenoid Saponins of Dianthus superbus var. longicalycinus Herbs1. · Planta medica
28.PMID: 21751357 (2011) — Sequencing cyclic peptides by multistage mass spectrometry. · Proteomics
29.PMID: 17340248 (1984) — Structure of Dianosides C, D, E and F, Triterpenoid Saponins of Dianthus superbus var. longicalycinus Herb1. · Planta medica
30.PMID: 25542429 (2017) — Isolation, characterization, and in rats plasma pharmacokinetic study of a new triterpenoid saponin from Dianthus superbus. · Archives of pharmacal research