Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 17 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Hydromethanolic extract (4 mg/mL) significantly reduced cell viability by 78.3% after 72 hours [PMID:35235421].
Aqueous extract (100 mg/kg) ameliorated hepatic steatosis and metabolic syndrome by reducing lipid accumulation, oxidative stress, and inflammation in rats on a hyperfatty diet [PMID:34335826].
Aqueous-methanol extract (100 mg/kg daily for 28 days) significantly amended fasting blood glucose levels in streptozotocin-induced diabetic rats [PMID:23052826].
Crude extract lowered glucose efflux by 39.4%-42.6% and ameliorated inflammatory markers in CaCo-2 and RAW 264.7 cell lines [PMID:38107090].
Ethanolic extract and taraxasteryl acetate exhibited antispasmodic and spasmogenic effects, suggesting possible lithuretic activity [PMID:9434612, PMID:17252378].
Synthèse des preuves
Sources PubMed
- 1.PMID: 35235421 (2022) — Effects of Golden Thistle (Scolymus hispanicus L.) on Cytotoxic Activity: Cell Cycle Arrest and Apoptotic Properties on the CaCo-2 Cell Line. · Journal of medicinal food
- 2.PMID: 38107090 (2023) — Golden thistle (Scolymus hispanicus L.) hydromethanolic extracts ameliorated glucose absorption and inflammatory markers in vitro. · Food science & nutrition
- 3.PMID: 34335826 (2021) — Scolymus hispanicus (Golden Thistle) Ameliorates Hepatic Steatosis and Metabolic Syndrome by Reducing Lipid Accumulation, Oxidative Stress, and Inflammation in Rats under Hyperfatty Diet. · Evidence-based complementary and alternative medicine : eCAM
- 4.PMID: 37375965 (2023) — Determination of Caffeoylquinic Acids Content by UHPLC in Scolymus hispanicus Extracts Obtained through Ultrasound-Assisted Extraction. · Plants (Basel, Switzerland)
- 5.PMID: 37111846