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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Tanacetum vulgare
A strongly aromatic European herb historically used as a vermifuge and insect repellent, now used with caution.
Tansy (Tanacetum vulgare) is a strongly aromatic herb historically used as a vermifuge and insect repellent, but its clinical use is severely limited by the neurotoxic and hepatotoxic monoterpene thujone. Modern research suggests mild anti-inflammatory and emmenagogue effects, but the narrow therapeutic index and risk of seizures, liver damage, and abortion restrict its application to low-dose, short-term use under expert guidance. The herb also contains parthenolide and camphor, which contribute to its pharmacological profile but also to its toxicity.
Thujone, the primary active compound, acts as a GABA-A receptor antagonist, reducing chloride ion conductance and leading to neuronal hyperexcitability and seizures. Parthenolide inhibits NF-κB activation and COX-2 expression, providing anti-inflammatory effects. Camphor stimulates cold-sensitive TRPM8 receptors and has mild analgesic properties. The emmenagogue effect is thought to involve uterine stimulation via thujone and other volatile constituents, possibly through modulation of prostaglandin synthesis. Tanacetin and other sesquiterpene lactones contribute to the herb's bitter tonic and digestive effects by stimulating gastric secretions.
A strongly aromatic European herb historically used as a vermifuge and insect repellent, now used with caution.
Tansy (Tanacetum vulgare) is a strongly aromatic herb historically used as a vermifuge and insect repellent, but its clinical use is severely limited by the neurotoxic and hepatotoxic monoterpene thujone. Modern research suggests mild anti-inflammatory and emmenagogue effects, but the narrow therapeutic index and risk of seizures, liver damage, and abortion restrict its application to low-dose, short-term use under expert guidance. The herb also contains parthenolide and camphor, which contribute to its pharmacological profile but also to its toxicity.
Thujone, the primary active compound, acts as a GABA-A receptor antagonist, reducing chloride ion conductance and leading to neuronal hyperexcitability and seizures. Parthenolide inhibits NF-κB activation and COX-2 expression, providing anti-inflammatory effects. Camphor stimulates cold-sensitive TRPM8 receptors and has mild analgesic properties. The emmenagogue effect is thought to involve uterine stimulation via thujone and other volatile constituents, possibly through modulation of prostaglandin synthesis. Tanacetin and other sesquiterpene lactones contribute to the herb's bitter tonic and digestive effects by stimulating gastric secretions.