Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Tansy acts as an anthelmintic primarily through its volatile oil component, thujone. This compound acts as a neurotoxin to parasites, effectively paralyzing intestinal worms such as roundworms and pinworms, which allows the body to expel them. Historically, it was followed by a purgative to ensure the parasites were removed before the thujone caused systemic toxicity in the host (Evidence Level: C/Traditional).
Is tansy safe to take during pregnancy?
No, tansy is strictly contraindicated during pregnancy and is considered unsafe. The herb contains thujone, which stimulates uterine contractions and has a historical reputation as an abortifacient. Ingestion can lead to miscarriage or fetal harm. Additionally, the neurotoxic effects of thujone pose significant risks to fetal development. It should be completely avoided by pregnant and nursing women (Evidence Level: C/Traditional).
What is the safe dosage for tansy tea?
Due to the risk of thujone toxicity, tansy should only be taken in very low doses. The standard recommendation for adults is 0.5 to 1 gram of dried herb per cup of boiling water, consumed as a tea. Usage must be short-term, typically limited to a few days, and should not exceed two weeks. The essential oil should never be ingested internally due to high toxicity (Evidence Level: Traditional).
Does tansy interact with any medications?
Yes, tansy has significant interaction potential. Because thujone lowers the seizure threshold, it may counteract the effectiveness of anticonvulsant medications like phenytoin or valproate. It also carries hepatotoxic risks, meaning it should be avoided alongside other liver-straining drugs or alcohol. Furthermore, its potential to affect blood clotting suggests caution when combined with anticoagulants like warfarin (Evidence Level: C/Theoretical).
Why is tansy considered toxic?
Tansy is considered toxic because of its high concentration of thujone, a monoterpene ketone. Thujone is a neurotoxin that can overstimulate the nervous system, leading to seizures, hallucinations, and muscle spasms. Chronic use or overdose can cause irreversible liver damage and liver failure. Historical records document fatalities resulting from attempts to use the herb for abortion, necessitating extreme caution even at low therapeutic doses (Evidence Level: C).
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Tansy (Tanacetum vulgare) is an herbaceous plant used in folk medicine for various ailments, containing bioactive compounds with antimicrobial and antioxidant properties [PMID:36679141, PMID:36839938].
Contexte
Tanacetum vulgare is a widespread invasive species in North America and a member of the Asteraceae family [PMID:41124138]. It exhibits significant intraspecific chemodiversity, forming distinct chemotypes based on terpenoid composition [PMID:37703504, PMID:37351733].
Usages traditionnels
Used in folk medicine for digestive problems, fevers, migraines, parasites, and as an insect repellent [PMID:36679141]. It has also been traditionally applied for headaches, rheumatism, respiratory, and neurological problems [PMID:39683883].
Composés actifs
Active substances include essential oils rich in oxygenated monoterpenes and sesquiterpenes [PMID:33244630], specifically alpha-thujone, beta-thujone, eucalyptol, sabinene, chrysanthenon, camphor, and linalool oxide acetate [PMID:37998837]. It also contains phenolic acids (chlorogenic acid, rosmarinic acid), flavonoids (luteolin-7-glucoside, quercetin), and pectin (tanacetan) [PMID:36839938, PMID:40680672, PMID:38190112].
Mécanisme d'action
The plant's essential oils and phenolic compounds provide antimicrobial and antioxidant activities [PMID:36679141, PMID:37653885]. Quercetin, present in tansy, exhibits anti-inflammatory, antibacterial, and immunomodulatory effects [PMID:40680672].
Preuves cliniques
Preuve DCognitive function and anxiety
In rats, a 200 mg/kg alcohol extract improved learning and memory, while a 1000 mg/kg dose resulted in anxiolytic-like behavior [PMID:39683883]
Extracts significantly reduced the survival of trophonts and theronts in vitro [PMID:33847089]
Preuve DTrichostrongylidae Nematodes (sheep)
Extracts demonstrated strong larvicidal activity in vitro [PMID:37443974]
Preuve DBacterial infections
Essential oil shows antibacterial efficiency against ESKAPE pathogens [PMID:37998837]
Sécurité et effets indésirables
Tansy can be toxic to livestock [PMID:41124138]. Thujone, found in the plant, is toxic in high concentrations [PMID:37653885]. It is also a known cause of Compositae dermatitis, an allergic contact dermatitis [PMID:12793186, PMID:3827282].
Synthèse des preuves
The available evidence consists primarily of in vitro studies, animal models (rats, mice, bees), and case reports of allergic reactions. There are no human clinical trials provided in the source material.
2.PMID: 36679141 (2023) — Physicochemical and Antibacterial Properties of Alginate Films Containing Tansy (Tanacetum vulgare L.) Essential Oil. · Polymers
3.PMID: 40680672 (2025) — The role of Quercetin in the treatment of kidney diseases: A comprehensive review. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
4.PMID: 37513392 (2023) — Antimicrobial and Apoptotic Efficacy of Plant-Mediated Silver Nanoparticles. · Molecules (Basel, Switzerland)
5.PMID: 41124138 (2025) — Fertilizer and fungicide reduce herbicide efficacy and enhance growth of invasive common tansy (Tanacetum vulgare). · PloS one
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
PMID: 36839938 (2023) — In Vitro Study of Biological Activity of Tanacetum vulgare Extracts. · Pharmaceutics
7.PMID: 39409806 (2024) — Changes in Selected Biochemical Markers of Honey Bees Exposed to Fermented Common Tansy Solution (Tanacetum vulgare L.). · Animals : an open access journal from MDPI
8.PMID: 33244630 (2021) — In vitro cultivation of tansy (Tanacetum vulgare L.): a tool for the production of potent pharmaceutical agents. · Protoplasma
9.PMID: 3827282 (1987) — Compositae dermatitis in childhood. · Archives of dermatology
10.PMID: 33847089 (2021) — Parasiticidal effects of Tanacetum vulgare extract against Ichthyophthirius multifiliis. · Polish journal of veterinary sciences
11.PMID: 32778187 (2021) — Repellent activity of Tanacetum parthenium (L.) and Tanacetum vulgare (L.) essential oils against Leptinotarsa decemlineata (Say). · Bulletin of entomological research
12.PMID: 37653885 (2023) — Chemical Profiling and Antioxidant Activity of Tanacetum vulgare L. Wild-Growing in Latvia. · Plants (Basel, Switzerland)
13.PMID: 37998837 (2023) — Antibacterial Efficiency of Tanacetum vulgare Essential Oil against ESKAPE Pathogens and Synergisms with Antibiotics. · Antibiotics (Basel, Switzerland)
14.PMID: 37055463 (2023) — Plant chemical variation mediates soil bacterial community composition. · Scientific reports
16.PMID: 37703504 (2023) — Chemodiversity in flowers of Tanacetum vulgare has consequences on a florivorous beetle. · Plant biology (Stuttgart, Germany)
17.PMID: 38361330 (2024) — The hidden diversity of vascular patterns in flower heads. · The New phytologist
18.PMID: 31983003 (2020) — Evaluation of tansy essential oil as a potential "green" alternative for gypsy moth control. · Environmental science and pollution research international
19.PMID: 34015423 (2021) — Tanacetum vulgare L. (Tansy) as an effective bioresource with promising pharmacological effects from natural arsenal. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
20.PMID: 37443974 (2023) — Anthelmintic Activity of Tanacetum vulgare L. (Leaf and Flower) Extracts against Trichostrongylidae Nematodes in Sheep In Vitro. · Animals : an open access journal from MDPI
21.PMID: 39683883 (2024) — Evaluation of the Influence of Tanacetum vulgare Extract on Cognitive Functions and Hippocampal BDNF Expression. · Molecules (Basel, Switzerland)
22.PMID: 41919583 (2026) — Organ-specific terpenoid responses in Tanacetum vulgare are chemotype-dependent. · Plant biology (Stuttgart, Germany)
23.PMID: 24011527 (2013) — Elicitors of tansy volatiles from cotton leafworm larval oral secretion. · Phytochemistry
24.PMID: 33593286 (2021) — Nectar-dwelling microbes of common tansy are attractive to its mosquito pollinator, Culex pipiens L. · BMC ecology and evolution
25.PMID: 37351733 (2023) — Inter-laboratory comparison of plant volatile analyses in the light of intra-specific chemodiversity. · Metabolomics : Official journal of the Metabolomic Society
26.PMID: 38190112 (2024) — Cryoprotective Effect of Pectin Tanacetan from Tanacetum vulgare L. · Biopreservation and biobanking
27.PMID: 33476494 (2020) — [The effect of pectin of tansy, Tanacetum vulgare L., on anxiety and overeating food rich in fats and sugars in mice in modelling binge eating]. · Voprosy pitaniia
28.PMID: 17269022 (1987) — A study on tansy chemotypes. · Planta medica
29.PMID: 22353002 (2012) — Safety and efficacy of Setarud (IMOD TM ) among people living with HIV/AIDS: a review. · Recent patents on anti-infective drug discovery
30.PMID: 38140435 (2023) — The Antioxidant Activity of Wild-Growing Plants Containing Phenolic Compounds in Latvia. · Plants (Basel, Switzerland)