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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Curcuma zanthorrhiza
The most important medicinal herb in Indonesian Jamu tradition, used for liver protection and digestive health.
Temulawak (Curcuma zanthorrhiza) is a cornerstone of Indonesian Jamu medicine, prized for its hepatoprotective and digestive benefits. Its primary active compounds, xanthorrhizol and curcumin, confer anti-inflammatory, antimicrobial, and choleretic properties. This monograph synthesizes traditional and modern evidence to guide clinical use.
Xanthorrhizol and curcumin modulate multiple pathways: they inhibit NF-κB and COX-2 to reduce inflammation, activate Nrf2 to enhance antioxidant defenses, and stimulate bile acid synthesis via FXR agonism. Curcumin also inhibits CYP2E1 and reduces oxidative stress in hepatocytes, while germacrone and bisacurone contribute to antimicrobial activity by disrupting bacterial cell membranes. These actions collectively support liver detoxification, bile flow, and gastrointestinal health.
The most important medicinal herb in Indonesian Jamu tradition, used for liver protection and digestive health.
Temulawak (Curcuma zanthorrhiza) is a cornerstone of Indonesian Jamu medicine, prized for its hepatoprotective and digestive benefits. Its primary active compounds, xanthorrhizol and curcumin, confer anti-inflammatory, antimicrobial, and choleretic properties. This monograph synthesizes traditional and modern evidence to guide clinical use.
Xanthorrhizol and curcumin modulate multiple pathways: they inhibit NF-κB and COX-2 to reduce inflammation, activate Nrf2 to enhance antioxidant defenses, and stimulate bile acid synthesis via FXR agonism. Curcumin also inhibits CYP2E1 and reduces oxidative stress in hepatocytes, while germacrone and bisacurone contribute to antimicrobial activity by disrupting bacterial cell membranes. These actions collectively support liver detoxification, bile flow, and gastrointestinal health.