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Lycopus lucidus
A TCM blood-invigorating herb used for dysmenorrhea, blood stasis, and edema.
Ze Lan (Lycopus lucidus) is a traditional Chinese medicinal herb used primarily for blood stasis, dysmenorrhea, and edema. Its key active compounds include lycopurin, luteolin, caffeic acid, and flavonoids, which contribute to its antiplatelet, diuretic, and anti-inflammatory properties. Evidence level C indicates limited clinical data, but traditional use is well-documented.
The antiplatelet effect is attributed to lycopurin and caffeic acid, which inhibit platelet aggregation via COX-1 and thromboxane A2 pathways. Luteolin and flavonoids exert anti-inflammatory actions by suppressing NF-κB activation and reducing pro-inflammatory cytokines. The diuretic effect is thought to involve modulation of renal aquaporins and electrolyte transport, though specific receptors are not fully characterized.
A TCM blood-invigorating herb used for dysmenorrhea, blood stasis, and edema.
Ze Lan (Lycopus lucidus) is a traditional Chinese medicinal herb used primarily for blood stasis, dysmenorrhea, and edema. Its key active compounds include lycopurin, luteolin, caffeic acid, and flavonoids, which contribute to its antiplatelet, diuretic, and anti-inflammatory properties. Evidence level C indicates limited clinical data, but traditional use is well-documented.
The antiplatelet effect is attributed to lycopurin and caffeic acid, which inhibit platelet aggregation via COX-1 and thromboxane A2 pathways. Luteolin and flavonoids exert anti-inflammatory actions by suppressing NF-κB activation and reducing pro-inflammatory cytokines. The diuretic effect is thought to involve modulation of renal aquaporins and electrolyte transport, though specific receptors are not fully characterized.