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This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Bael fruit (Aegle marmelos) is a nutrient-rich fruit of the Rutaceae family used extensively in traditional medicine for its pharmacological activities, including antidiarrheal, antioxidant, and antidiabetic properties [PMID:36142805, PMID:33159390].
Background
Aegle marmelos (L.) Correa, commonly known as Bael, is a fruit tree native to the Indian subcontinent and Southeast Asia [PMID:32442219, PMID:37026028]. It is a member of the Rutaceae family and is widely cultivated in tropical and subtropical regions [PMID:36142805, PMID:33159390].
Traditional uses
In Ayurveda, Bael is used to treat chronic diarrhea, dysentery, stomach ache, and peptic ulcers [PMID:23089553, PMID:29709412]. Extracts from the bark, leaves, or roots are traditionally used as laxatives, febrifuges, and expectorants, and are applied in cases of ophthalmia, deafness, inflammations, catarrh, diabetes, and asthmatic complaints [PMID:23089553].
Active compounds
The fruit contains carbohydrates, proteins, minerals, vitamins, and phytochemicals such as alkaloids, flavonoids, and phenolic acids (protocatechuic, gallic, and ellagic acids) [PMID:36142805]. It is also a significant source of mucilaginous polysaccharides containing galactose and glucuronic acid [PMID:38726405], as well as fibers, carotenoids, terpenoids, and coumarins [PMID:33159390].
Mechanism of action
Bael fruit extracts may attenuate colitis by restoring the intestinal mucosal barrier and alleviating inflammation through the modulation of gut microbiota [PMID:41273865]. Its radioprotective effects are attributed to antioxidant compounds that counter free radicals generated by ionizing radiation [PMID:20932194].
Clinical evidence
Evidence DUlcerative Colitis
Aqueous, ethanolic, and hydroalcoholic extracts of A. marmelos fruit effectively attenuated DSS-induced colitis in mice by restoring cytokine levels and tight junction proteins [PMID:41273865]
Evidence DBreast Cancer
Ethanolic fruit pulp extract (200 mg/kg b.w./day) showed anticancer activity against DMBA-induced breast cancer in rats [PMID:33093498]
Evidence DDiuresis
Both root and leaf extracts increased urine output in experimental rats, with the root sample showing maximum output [PMID:26664244]
Safety & adverse effects
An in vitro study on human gingival fibroblast cells showed that an ethanolic extract of Bael leaves exhibited minimal cytotoxicity at a concentration of 6.3 μl/ml, though viability decreased as exposure time increased [PMID:39600753].
Evidence summary
The current evidence is primarily based on in vitro studies, animal models (mice and rats), and literature reviews. There is a lack of human clinical trial data in the provided abstracts.
PubMed sources
1.PMID: 36142805 (2022) — Aegle marmelos (L.) Correa: An Underutilized Fruit with High Nutraceutical Values: A Review. · International journal of molecular sciences
3.PMID: 23089553 (2013) — Aegle marmelos (L.) Correa (Bael) and its phytochemicals in the treatment and prevention of cancer. · Integrative cancer therapies
4.PMID: 37026028 (2023) — Phytochemical and biological review of Aegle marmelos Linn. · Future science OA
5.PMID: 37960942 (2023) — Bael (Aegle marmelos L. Correa) fruit extracts encapsulated alginate nanoparticles as a potential dietary supplement with improved bioactivities.
Government sources
No direct government monograph is available for this herb. The content below is AI-generated and has not been verified against an authoritative government source. Use the search links to check official sources before relying on this information.
6.PMID: 34538927 (2021) — Indian goose berry fortified, anti-oxidant rich bael (Aegle marmelos) fermented beverage. · Journal of food science and technology
7.PMID: 33159390 (2021) — Bioactive compounds of Aegle marmelos L., medicinal values and its food applications: A critical review. · Phytotherapy research : PTR
8.PMID: 29709412 (2018) — Phytochemical profile and pharmacological activity of Aegle marmelos Linn. · Journal of integrative medicine
9.PMID: 40854911 (2025) — Genotypic diversity and nutritional profiling of Bael [Aegle marmelos (L.) Correa] genotypes in India. · Scientific reports
11.PMID: 32442219 (2020) — Assessment of the elite accessions of bael [Aegle marmelos (L.) Corr.] in Sri Lanka based on morphometric, organoleptic, and elemental properties of the fruits and phylogenetic relationships. · PloS one
12.PMID: 38278399 (2024) — Polysaccharide mediated nanodrug delivery: A review. · International journal of biological macromolecules
13.PMID: 39098938 (2024) — Genetic diversity and population structure of Bael [Aegle marmelos (L.) Correa] genotypes using molecular markers in the North-Western plains of India. · Scientific reports
14.PMID: 40866800 (2025) — Genetic diversity assessment of bael (Aegle marmelos) varieties using morphometric, yield, and quality traits under semi-arid conditions. · BMC plant biology
15.PMID: 34229590 (2022) — Indian Indigenous Fruits as Radioprotective Agents: Past, Present and Future. · Anti-cancer agents in medicinal chemistry
16.PMID: 39435370 (2024) — The Dawn till Dusk of phytopharmaceuticals. · Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
17.PMID: 39600753 (2024) — Evaluation of the Effect of Aegle marmelos (Bael Leaf) Extract on Human Fibroblast Viability: An In Vitro Study. · Cureus
18.PMID: 20932194 (2010) — Radioprotective effects of Aegle marmelos (L.) Correa (Bael): a concise review. · Journal of alternative and complementary medicine (New York, N.Y.)
19.PMID: 40177020 (2025) — Morphology and pomological characterization of bael [Aegle marmelos (L.) Correa] genotypes for climate change mitigation under north-western Himalayas. · Frontiers in plant science
20.PMID: 38468524 (2025) — Phyto-pharmacological Potential of Aegle marmelos (L.) for Neurological Disorders: Progress and Prospects. · Recent advances in food, nutrition & agriculture
21.PMID: 29239790 (2018) — Anti-inflammatory profile of Aegle marmelos (L) Correa (Bilva) with special reference to young roots grown in different parts of India. · Journal of Ayurveda and integrative medicine
22.PMID: 23723639 (2012) — A critical review on two types of Laghupanchamula. · Ayu
23.PMID: 41273865 (2025) — Aegle marmelos effectively attenuates DSS-induced colitis by restoring intestinal mucosal barrier and alleviating inflammation through modulation of gut microbiota in mice. · Phytomedicine : international journal of phytotherapy and phytopharmacology
24.PMID: 36515023 (2023) — A Review on Herbal Drugs Used in the Treatment of Peptic Ulcer. · Current drug discovery technologies
25.PMID: 33093498 (2020) — Therapeutic effect of Aegle marmelos fruit extract against DMBA induced breast cancer in rats. · Scientific reports
26.PMID: 29615046 (2018) — Phytochemical composition, antilipidemic and antihypercholestrolemic perspectives of Bael leaf extracts. · Lipids in health and disease
27.PMID: 26664244 (2014) — A comparative experimental study to evaluate Mutrala (diuretic) activity of Bilva Moola and Patra (Aegle marmelos Corr.). · Ayu
28.PMID: 32851864 (2021) — Constituents of Aegle marmelos from Myanmar. · Journal of Asian natural products research