PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous extract showed a strong decline in proinflammatory cytokine expression, downregulating COX-2 (57%), iNOS (41%), TNF-α (29%), IL-1β (32%), IL-6 (21%), and IL-8 (35%) in HaCaT cells [PMID:32373312]
Luteolin and colchicine isolated from B. davidii exhibited potent inhibitory activities and induced apoptosis in human gastric cancer cell lines [PMID:22938042]
Linarin dose-dependently increased cell viability and reduced apoptotic cells in PC12 cells [PMID:21652214]
Evidence summary
PubMed sources
- 1.PMID: 36119599 (2022) — The mystery of the butterfly bush Buddleja davidii: How are the butterflies attracted? · Frontiers in plant science
- 2.PMID: 24082630 (2012) — Quantitative determination of total and individual flavonoids in stems and leaves of Buddleja davidii and Buddleja albiflora. · Pharmacognosy magazine
- 3.PMID: 40417216 (2025) — Cosmeceutical application of extracts from the flowers, stems, and leaves of Buddleja davidii grown at different altitudes. · Frontiers in pharmacology
- 4.PMID: 19548780 (2009) — Antioxidant phenylpropanoid glycosides from Buddleja davidii. · Journal of enzyme inhibition and medicinal chemistry
- 5.PMID: 26330885 (2015) — Linarin Inhibits the Acetylcholinesterase Activity In-vitro and Ex-vivo.