PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Clove oil is a popular natural cure due to its anti-inflammatory and analgesic qualities [PMID:38163240]
In vitro activity and biofilm inhibition (up to 90%) against E. coli, S. aureus, and K. pneumoniae [PMID:41163998]
Oral clove extract and eugenol significantly alleviated psoriasiform lesions and reduced epidermal thickness in mouse models by modulating the IL-36/IL-17A axis [PMID:42272840]
Nanoencapsulated clove oil alleviated acetic acid-induced ulcerative colitis in rats by influencing redox, NF-κB/iNOS, and Keap1/Nrf2/HO-1 pathways [PMID:41055815]
Clove bud oil alone or with imipenem healed wounds faster and reduced microbial load in rat models [PMID:36500645]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 34770801 (2021) — Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health. · Molecules (Basel, Switzerland)
- 2.PMID: 32019140 (2020) — Syzygium aromaticum L. (Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological and Toxicological Activities. · Biomolecules
- 3.PMID: 25182278 (2014) — Clove (Syzygium aromaticum): a precious spice. · Asian Pacific journal of tropical biomedicine
- 4.PMID: 38163240 (2024) — Bioactive properties of clove (Syzygium aromaticum) essential oil nanoemulsion: A comprehensive review. · Heliyon
- 5.PMID: 34885992 (2021)