This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Hydrastis canadensis
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
This herb may interact with medications you are taking. Review the interactions table below and consult your healthcare provider before use.
Goldenseal is a perennial herb native to North America, traditionally used by Native Americans for infections and digestive complaints. It contains berberine and hydrastine as primary active compounds. Due to overharvesting, it is now considered at risk in the wild, and cultivated sources are preferred.
Goldenseal is a perennial herb native to North America, traditionally used by Native Americans for infections and digestive complaints. It contains berberine and hydrastine as primary active compounds. Due to overharvesting, it is now considered at risk in the wild, and cultivated sources are preferred. Key active compounds include Berberine, Hydrastine, Canadine.
Berberine, along with Hydrastine and Canadine, are the primary bioactive compounds in Goldenseal. These compounds stimulates digestive enzyme secretion and GI motility.
Upper respiratory infections
Supported by clinical evidence; more large-scale trials would strengthen findings
Digestive infections
Supported by clinical evidence; more large-scale trials would strengthen findings
Urinary tract infections
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Eye infections (eyewash)
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Canker sores
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Eye infections
Based on traditional use; clinical evidence limited
Digestive aid
Based on traditional use; clinical evidence limited
Skin conditions
Based on traditional use; clinical evidence limited
| Drug | Severity | Description |
|---|---|---|
| Metformin | Moderate | Berberine in goldenseal may enhance blood sugar-lowering effects of metformin. |
| Cyclosporine | Severe | Goldenseal (berberine) may significantly increase cyclosporine blood levels, increasing toxicity risk. |
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