PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Adlay polyphenol decreased lipid accumulation in HepG2 cells and reduced body weight, liver weight, hepatic triglycerides, and serum glucose in high-fat diet-fed mice [PMID:36214059]
Dehulled adlay diet attenuated plasma glucose, insulin levels, and HOMA-IR in streptozotocin/high-fat diet-induced diabetic rats [PMID:38526822]
A synthesized peptide (GAAGGAF) derived from Coix glutelin reduced systolic blood pressure in spontaneously hypertensive rats [PMID:28098801]
Adlay diet (30%) and water extract reversed decreased bone alkaline phosphatase activity, calcium contents, and bone mineral density in ovariectomized mice [PMID:24716168]
Ethanolic extracts and sprout extracts induced cell cycle arrest and apoptosis in human breast (MCF-7), cervical (HeLa), and endometrial cancer cell lines [PMID:35807238, 31729992, 33807346]
Evidence summary
PubMed sources
- 1.PMID: 24716141 (2012) — Adlay ( yì yĭ; "soft-shelled job's tears"; the seeds of Coix lachryma-jobi L. var. ma-yuen Stapf) is a Potential Cancer Chemopreventive Agent toward Multistage Carcinogenesis Processes. · Journal of traditional and complementary medicine
- 2.PMID: 35707908 (2023) — Two new amides from the seeds of Coix lacryma-jobi var. lacryma-jobi. · Natural product research
- 3.PMID: 35807238 (2022) — Adlay Seed (Coix lacryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract Fractions and Subfractions Induce Cell Cycle Arrest and Apoptosis in Human Breast and Cervical Cancer Cell Lines. · Molecules (Basel, Switzerland)
- 4.PMID: 36214059 (2022) — Adlay (Coix lacryma-jobi L.) Polyphenol Improves Hepatic Glucose and Lipid Homeostasis through Regulating Intestinal Flora via AMPK Pathway. · Molecular nutrition & food research
- 5.PMID: 37631186