PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Seed oil protects against mitochondrial damages [PMID:37324897] and attenuates alterations in testicular biochemistry and histology [PMID:35846473], restoring mitochondrial functions by modulating mitochondrial enzymes [PMID:39479659].
Seed oil (CMSO) demonstrated therapeutic potential in alleviating BPA-induced dyslipidemia and adipokine dysfunction in male rats [PMID:37324904].
Seed oil shields rats from toxicity by modulating redox imbalance and iNOS/IL-β1 signaling [PMID:39897807].
Extracts reversed changes in glucose levels, lipid peroxidation, and super-oxide dismutase activity, and decreased body weight in mice [PMID:33048776].
Cucumeropsis mannii melon seed husk extract (MSHE) silica nanoparticles increased levels of plasma gonadotropin hormones (FSH, LH) and testosterone in rats exposed to Ni and Al [PMID:39979503].
Evidence summary
PubMed sources
- 1.PMID: 37324897 (2023) — Cucumeropsis mannii seed oil protects against Bisphenol A-induced testicular mitochondrial damages. · Food science & nutrition
- 2.PMID: 37324904 (2023) — Cucumeropsis mannii seed oil ameliorates Bisphenol-A-induced adipokines dysfunctions and dyslipidemia. · Food science & nutrition
- 3.PMID: 37303580 (2023) — Biodiesel potential of Cucumeropsis mannii (white melon) seed oil: A neglected and underutilized resource in Nigeria. · Heliyon
- 4.PMID: 37167260 (2023) — Flour nutritional profile, and soxhlet-extracted oil physicochemical breakdown-storage performance of white melon (Cucumeropsis mannii Naudin) seed varieties from Southeast Nigeria. · PloS one
- 5.PMID: 39479659