PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Polysaccharides (COP70-1 and COP90-1) promote the proliferation and osteoblastic differentiation of MC3T3-E1 cells and alleviate ovariectomy-induced osteoporosis in rats [PMID:37473884, PMID:28821095].
Rhizome extract showed protective effects against heat stress-induced spermatogenesis complications in male mice [PMID:37185736].
Alcoholic extract demonstrated estrogenic activity in ovariectomized rats, affecting vaginal cornification and uterine weight [PMID:17900835].
Extracts ameliorated urotoxicity, nephrotoxicity, and neurotoxicity induced by cyclophosphamide in experimental animals [PMID:26424815, PMID:25948959].
Extracts showed therapeutic effects on noise-induced hearing loss in mice [PMID:21544731] and protected auditory cells (HEI-OC1) from cisplatin-induced damage [PMID:23548130].
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 36775079 (2023) — Jinfeng pills ameliorate premature ovarian insufficiency induced by cyclophosphamide in rats and correlate to modulating IL-17A/IL-6 axis and MEK/ERK signals. · Journal of ethnopharmacology
- 2.PMID: 23562803 (2013) — Medicinal plants of genus Curculigo: traditional uses and a phytochemical and ethnopharmacological review. · Journal of ethnopharmacology
- 3.PMID: 36429955 (2022) — Toxicity Assessment of Curculigo orchioides Leaf Extract Using Drosophila melanogaster: A Preliminary Study. · International journal of environmental research and public health
- 4.PMID: 22974543 (2012) — Curculigo orchioides (Xian Mao) modifies the activity and protein expression of CYP3A in normal and Kidney-Yang Deficiency model rats. · Journal of ethnopharmacology
- 5.PMID: 37185736