PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ingestion of 7.5 g/d resulted in nonsignificant decreases in hot flash symptomatology; however, 25 g/d increased tumor apoptotic index and decreased HER2 expression and cell proliferation [PMID:24013641]
Results are inconsistent across studies, though three studies revealed a significant reduction in hunger perception and appetite [PMID:35916016]
A systematic review and meta-analysis were conducted to assess effects on fasting blood glucose, HbA1c, and HOMA-IR [PMID:35843472]
Flax is associated with reducing cholesterol levels and relaxing smooth muscle cells in arteries to increase blood flow [PMID:30378485, PMID:40628690]
Safety & adverse effects
Pregnancy & lactation
Evidence summary
PubMed sources
- 1.PMID: 30000955 (2006) — Anaphylaxis to Linum. · Allergologia et immunopathologia
- 2.PMID: 32294947 (2020) — Flax (Linum usitatissimum L.): A Potential Candidate for Phytoremediation? Biological and Economical Points of View. · Plants (Basel, Switzerland)
- 3.PMID: 36193986 (2024) — Health benefits of flaxseed and its peptides (linusorbs). · Critical reviews in food science and nutrition
- 4.PMID: 35870878 (2022) — The flax genome reveals orbitide diversity. · BMC genomics
- 5.PMID: 37570965 (2023) — Overview and Management of the Most Common Eukaryotic Diseases of Flax (Linum usitatissimum). · Plants (Basel, Switzerland)