PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
In healthy non-diabetic human subjects, the fruit demonstrated a low glycemic index (5.34) with modest hypoglycemic activity [PMID:23261731].
Ethanolic fruit extract reduced blood glucose and pancreatic MDA levels while increasing liver glycogen in STZ-induced diabetic rats [PMID:26347423]. Stem bark extract also showed antidiabetic and antihyperlipidemic properties in alloxan-induced diabetic rats [PMID:27538464].
Methanol extract of leaves provided protection against pentylenetetrazole and maximal electroshock induced seizures and showed anxiolytic activity in mice [PMID:35933940]. Fruit juice (20-30% dilutions) diminished anxiety, depression, and scopolamine-induced memory impairment in rats [PMID:33521033].
Lyophilized fruit powder (200-400 mg/kg) effectively reduced renal biomarkers, blood urea nitrogen, and creatinine in cisplatin-induced acute kidney injury rats [PMID:40291032].
Fruit extract (250-500 mg/kg) decreased serum AST, ALT, LDH, and CKMB in isoproterenol-induced myocardial injury and reduced carrageenan-induced paw edema [PMID:36861237].
Evidence summary
PubMed sources
- 1.PMID: 32320069 (2020) — Nutraceutical perspectives and value addition of phalsa (Grewia asiatica L.): A review. · Journal of food biochemistry
- 2.PMID: 34229590 (2022) — Indian Indigenous Fruits as Radioprotective Agents: Past, Present and Future. · Anti-cancer agents in medicinal chemistry
- 3.PMID: 38312640 (2024) — Phytochemical and pharmacological characteristics of phalsa (Grewia asiatica L.): A comprehensive review. · Heliyon
- 4.PMID: 36348773 (2022) — Selection of promising accessions of phalsa (Grewia asiatica L.) based on fruit-related traits. · Food science & nutrition
- 5.PMID: 37464170 (2024) — Tracking the Variations in Trace Elements, Some Nutrients, Phenolics, and Anthocyanins in Grewia asiatica L. (Phalsa) at Different Fruit Development Stages.